Aprepitant (MK-0869)

Name: Aprepitant (MK-0869); MyBioSource
Brand: MyBioSource
SKU: MBS3602607
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602607

A potent, orally active, long-acting human NK-1 receptor (substance P receptor) antagonist with IC50 of 0.09 nM. More details

$235 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Aprepitant, Biochemical

Full Product Name

Aprepitant

Product Synonym Names

MK-0869; MK-869; L-754030

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

534.4266

Suitability

10mM in DMSO

Target

Neurokinin Receptor

Receptor

NK1

Chemical Name

3H-1, 2, 4-Triazol-3-one, 5-[[(2R, 3S)-2-[(1R)-1-[3, 5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1, 2-dihydro

SMILES

O=C1NNC(CN2[C@@H](C3=CC=C(F)C=C3)[C@@H](O[C@@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)OCC2)=N1

Molecular Formula

C23H21F7N4O3

CAS Number

170729-80-3

Product Categories/Family for Aprepitant biochemical

Chemotherapeutic; GPCR/G Protein; Cancer

Product References and Citations for Aprepitant biochemical

1. Kramer MS, et al. Science. 1998 Sep 11; 281 (5383):1640-5.
2. Hale JJ, et al. J Med Chem. 1998 Nov 5; 41 (23):4607-14.
3. Tattersall FD, et al. Neuropharmacology. 2000 Feb 14; 39 (4):652-63.

Other Notes

Small volumes of Aprepitant biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Aprepitant purchase

MBS3602607 is a biochemical targeting Aprepitant.