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AZD-3759

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602405

A potent, oral active, BBB-penetrating EGFR inhibitor (IC50=7.2 nM, L858R pEGFR). More details

$215 / 1mL*10mM (in DMSO) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AZD-3759, Biochemical
Full Product Name
AZD-3759
Product Synonym Names
AZD-3759
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
459.9011
Suitability
10mM in DMSO
Target
EGFR
Receptor
EGFR (exon19Del); EGFR (L858R); EGFR (WT)
Chemical Name
1-Piperazinecarboxylic acid, 2, 4-dimethyl-, 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl ester, (2R)
SMILES
O=C(N1[C@H](C)CN(C)CC1)OC2=CC3=C(NC4=CC=CC(Cl)=C4F)N=CN=C3C=C2OC
Molecular Formula
C22H23ClFN5O3
CAS Number
1626387-80-1

Product Categories/Family for AZD-3759 biochemical

Lung Cancer; Angiogenesis; Cancer

Structure of AZD-3759 biochemical

AZD-3759 Biochemical – Cat# MBS3602405

Product References and Citations for AZD-3759 biochemical

1. Zeng Q, et al. J Med Chem. 2015 Oct 22; 58 (20):8200-15.
2. Yang Z, et al. Sci Transl Med. 2016 Dec 7; 8 (368):368ra172.
3. Tan CS, et al. Lung Cancer. 2016 Mar; 93:59-68.

Other Notes

Small volumes of AZD-3759 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZD-3759 purchase

MBS3602405 is a biochemical targeting AZD-3759.
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