Brigatinib (AP-26113)

Name: Brigatinib (AP-26113); MyBioSource
Brand: MyBioSource
SKU: MBS3600706
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600706

Brigatinib (AP-26113, AP26113) is a potent, selective, second generation ALK inhibitor with IC50 of 0.62 nM. More details

$215 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Brigatinib, Biochemical

Full Product Name

Brigatinib

Product Synonym Names

AP-26113; AP26113

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

584.0924

Suitability

10mM) in Ethanol

Target

ALK

Receptor

ALK; EGFR (C797S/del19); FLT3; IGF-1R; ROS1

Chemical Name

2, 4-Pyrimidinediamine, 5-chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]

SMILES

CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)NC5=CC=CC=C5P(=O)(C)C)Cl)OC

Molecular Formula

C29H39ClN7O2P

CAS Number

1197953-54-0

Product Categories/Family for Brigatinib biochemical

Lung Cancer; Angiogenesis; Cancer

Product References and Citations for Brigatinib biochemical

1. Katayama R, et al. Proc Natl Acad Sci U S A. 2011 May 3; 108 (18):7535-40.
2. Ceccon M, et al. Mol Cancer Res. 2013 Feb; 11 (2):122-32.
3. Ceccon M, et al. Mol Cancer Res. 2015 Apr; 13 (4):775-83.
4. Fontana D, et al. Cancer Med. 2015 Jul; 4 (7):953-65.

Other Notes

Small volumes of Brigatinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Brigatinib purchase

MBS3600706 is a biochemical targeting Brigatinib.