CHIR-99021 (CT99021)

Name: CHIR-99021 (CT99021); MyBioSource
Brand: MyBioSource
SKU: MBS3603746
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603746

A potent, specific GSK-3 inhibitor with IC50 of 5 nM and 10 nM for GSK3beta and GSK3alpha, respectively. More details

$220 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CHIR-99021, Biochemical

Full Product Name

CHIR-99021

Product Synonym Names

CT99021; CHIR99021; CHIR 99021; CT-99021

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

465.3379

Suitability

DMSO: >=5.1mg/mL

Target

GSK-3

Receptor

GSK-3alpha; GSK-3beta

Chemical Name

3-Pyridinecarbonitrile, 6-[[2-[[4-(2, 4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]

SMILES

CC1=CN=C(N1)C1=CN=C(NCCNC2=NC=C(C=C2)C#N)N=C1C1=C(Cl)C=C(Cl)C=C1

Molecular Formula

C22H18Cl2N8

CAS Number

252917-06-9

Product Categories/Family for CHIR-99021 biochemical

PI3K/Akt/mTOR signaling; Cancer

Product References and Citations for CHIR-99021 biochemical

1. Ying QL, et al. Nature. 2008 May 22; 453 (7194):519-23.
2. Ring DB, et al. Diabetes. 2003 Mar; 52 (3):588-95.
3. Bennett CN, et al. J Biol Chem. 2002 Aug 23; 277 (34):30998-1004.
4. Li W, et al. Stem Cells. 2009 Dec; 27 (12):2992-3000.

Other Notes

Small volumes of CHIR-99021 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CHIR-99021 purchase

MBS3603746 is a biochemical targeting CHIR-99021.