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Cu(II)GTSM

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5800969

Cu(II)GTSM, a cell-permeable Cu-complex, significantly inhibits GSK3beta. Cu(II)GTSM inhibits Amyloid-beta oligomers (AbetaOs) and decreases tau phosphorylation. Cu(II)GTSM also decreases the abundance of Amyloid-beta trimers. Cu(II)GTSM is a potential… More details

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Product Overview

Online Datasheet in PDF
Product Name
Cu(II)GTSM, Biochemical
Full Product Name
Cu(II)GTSM
Product Gene Name
Cu(II)GTSM biochemical
Purity/Purification
98%
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
Molecular Weight
178.187
CAS
68341-14-0
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
Cu(II)GTSM decreases brain Abeta trimer levels in AD mice, and can reverse cognitive deficits in APP/PS1 transgenic AD mice[2]. Animal Model: AD mice (K670N, M671L; 5-6 months old)[2]. Dosage: 10 mg/kg. Administration: Daily; p.o. Result: Restores cognitive performance of the AD mice to levels expected for healthy, cognitively normal mice.

Structure of Cu(II)GTSM biochemical

(E)-3-(4-Methoxyphenyl)acrylic acid, CAS 943-89-5
Cu(II)GTSM Biochemical – Cat# MBS5800969

Structure of Cu(II)GTSM biochemical

(E)-3-(4-Methoxyphenyl)acrylic acid, CAS 943-89-5
Cu(II)GTSM Biochemical, Structure – Cat# MBS5800969

Product References and Citations for Cu(II)GTSM biochemical

1. Sirichan Tachai, et al. Uncommon secondary metabolites from Etlingera pavieana rhizomes. Nat Prod Res. 2016 Oct;30(19):2215-9.

Other Notes

Small volumes of Cu(II)GTSM biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cu(II)GTSM purchase

MBS5800969 is a biochemical targeting Cu(II)GTSM.
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