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E6446

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3607194

E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro. More details

$340 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
E6446, Biochemical
Full Product Name
E6446
Product Synonym Names
E6446; E 6446; E-6446
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
449.6
Target
Dopamine Receptor
Receptor
TLR7; TLR9
Chemical Name
6-(3-Pyrrolidin-1-yl-propoxy)-2-[4-(3-pyrrolidin-1-yl-propoxy)-phenyl]-benzooxazole
SMILES
C1CCN(C1)CCCOc1ccc(cc1)c1nc2c(o1)cc(cc2)OCCCN1CCCC1
Molecular Formula
C27H35N3O3
CAS Number
1219925-73-1

Product Categories/Family for E6446 biochemical

GPCR/G Protein; Inflammation/Immunology

Structure of E6446 biochemical

E6446 Biochemical – Cat# MBS3607194

Product References and Citations for E6446 biochemical

1: Dias AA, et al. DNA Sensing via TLR-9 Constitutes a Major Innate Immunity Pathway Activated during Erythema Nodosum Leprosum. J Immunol. 2016 Sep 1; 197 (5):1905-13.

Other Notes

Small volumes of E6446 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for E6446 purchase

MBS3607194 is a biochemical targeting E6446.
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