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MK-0812

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605361

A potent CCR2 specific antagonist that blocks MCP-1 mediated response with an IC50 of 3.2 nM. More details

$1315 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MK-0812, Biochemical
Full Product Name
MK-0812
Product Synonym Names
MK 0812; MK0812
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
469.5403
Suitability
10mM in DMSO
Target
Chemokine Receptor
Receptor
Chemokine Receptor
Chemical Name
D-erythro-Pentitol, 1, 5-anhydro-2, 3-dideoxy-3-[[(1R, 3S)-3-[[7, 8-dihydro-3-(trifluoromethyl)-1, 6-naphthyridin-6(5H)-yl]carbonyl]-3-(1-methylethyl)cyclopentyl]amino]-4-O-methyl
SMILES
CC(C)[C@@]1(CC[C@H](C1)N[C@H]2CCOC[C@H]2OC)C(=O)N3CCC4=NC=C(C=C4C3)C(F)(F)F
Molecular Formula
C24H34F3N3O3
CAS Number
624733-88-6

Product Categories/Family for MK-0812 biochemical

Multiple Sclerosis; GPCR/G Protein; Inflammation/Immunology

Structure of MK-0812 biochemical

Mk-0812 Biochemical – Cat# MBS3605361

Product References and Citations for MK-0812 biochemical

1. Wisniewski T, et al. J Immunol Methods. 2010 Jan 31; 352 (1-2):101-10.
2. O'Brien PD, et al. Diabetes Obes Metab. 2017 Mar 23. doi: 10.1111/dom.12950.
3. Min SH, et al. Biochem Biophys Res Commun. 2010 Jan 1; 391 (1):1080-6.

Other Notes

Small volumes of MK-0812 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-0812 purchase

MBS3605361 is a biochemical targeting MK-0812.
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