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MK-591

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602014

A potent, orally active leukotriene biosynthesis inhibitor that acts by inhibiting 5-lipoxygenase activating protein (FLAP) with IC50 of 1.6 nM in a FLAP binding assay. More details

$715 / 50 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MK-591, Biochemical
Full Product Name
MK-591
Product Synonym Names
Quiflapon sodium; MK-0591; L-686708
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
609.1531
Suitability
10mM in DMSO
Target
FLAP
Receptor
FLAP
Chemical Name
1H-Indole-2-propanoic acid, 1-[(4-chlorophenyl)methyl]-3-[(1, 1-dimethylethyl)thio]-alpha, alpha-dimethyl-5-(2-quinolinylmethoxy)-, sodium salt(1:1)
SMILES
CC(C)(C)SC1=C(N(C2=C1C=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)CC5=CC=C(C=C5)Cl)CC(C)(C)C(=O)[O-].[Na+]
Molecular Formula
C34H34ClN2NaO3S
CAS Number
147030-01-1

Product Categories/Family for MK-591 biochemical

Asthma; Immunology/Inflammation; Inflammation/Immunology

Structure of MK-591 biochemical

Mk-591 Biochemical – Cat# MBS3602014

Product References and Citations for MK-591 biochemical

1. Brideau C, et al. Can J Physiol Pharmacol. 1992 Jun; 70 (6):799-807.
2. Mienard L, et al. Can J Physiol Pharmacol. 1992 Jun; 70 (6):808-13.
3. Tagari P, et al. J Pharmacol Exp Ther. 1993 Apr; 265 (1):416-25.

Other Notes

Small volumes of MK-591 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-591 purchase

MBS3602014 is a biochemical targeting MK-591.
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