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MK-8722

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601645

A potent, selective, allosteric pan-AMPK activator with EC50 of 1-60 nM for all 12 mammalian AMPK isoforms. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MK-8722, Biochemical
Full Product Name
MK-8722
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
449.891
Suitability
DMSO: >=62.5mg/mL (138.92mM)
Target
AMPK
Receptor
AMPK
Chemical Name
(3R, 3aR, 6R, 6aR)-6-((6-([1, 1'-biphenyl]-4-yl)-7-chloro-3H-imidazo[4, 5-b]pyridin-2-yl)oxy)hexahydrofuro[3, 2-b]furan-3-ol
SMILES
ClC1=C2C(NC(O[C@@H]3CO[C@@]4([H])[C@]3([H])OC[C@H]4O)=N2)=NC=C1C5=CC=C(C6=CC=CC=C6)C=C5
Molecular Formula
C24H20ClN3O4
CAS Number
1394371-71-1

Product Categories/Family for MK-8722 biochemical

Membrane Transporter/Ion Channel; Metabolic Disease

Structure of MK-8722 biochemical

Mk-8722 Biochemical – Cat# MBS3601645

Product References and Citations for MK-8722 biochemical

1. Myers RW, et al. Science. 2017 Aug 4; 357 (6350):507-511.
2. Danqing Feng, et al. ACS Med. Chem. Lett. DOI: 10.1021/acsmedchemlett.7b00417

Other Notes

Small volumes of MK-8722 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-8722 purchase

MBS3601645 is a biochemical targeting MK-8722.
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