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PD0325901

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604344

MBS3604344 is a biochemical targeting PD0325901. A selective, non ATP-competitive MEK inhibitor with IC50 of 0.33 nM. More details

$235 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PD0325901, Biochemical
Full Product Name
PD0325901
Product Synonym Names
PD 0325901; PD325901; PD-0325901
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
482.1931
Suitability
DMSO: >=56mg/mL
Target
MEK
Receptor
MEK
Chemical Name
Benzamide, N-[(2R)-2, 3-dihydroxypropoxy]-3, 4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]
SMILES
O=C(NOC[C@H](O)CO)C1=CC=C(F)C(F)=C1NC2=CC=C(I)C=C2F
Molecular Formula
C16H14F3IN2O4
CAS Number
391210-10-9

Product Categories/Family for PD0325901 biochemical

Brain Cancer; MAPK/ERK Signaling; Cancer

Structure of PD0325901 biochemical

PD0325901 Biochemical – Cat# MBS3604344

Product References and Citations for PD0325901 biochemical

1. Barrett SD, et al. Bioorg Med Chem Lett. 2008 Dec 15; 18 (24):6501-4.
2. Ciuffreda L, et al. Neoplasia. 2009 Aug; 11 (8):720-31.
3. Henderson YC, et al. Mol Cancer Ther. 2010 Jul; 9 (7):1968-76.

Other Notes

Small volumes of PD0325901 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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