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PF-06263276

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601766

PF-06263276 (PF06263276, PF 6263276) is a potent, selective pan JAK inhibitor with IC50 of 2.2, 23.1, 59.9 and 29.7 nM for JAK1, JAK2, JAK3, and TYK2, respectively. More details

$715 / 50 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PF-06263276, Biochemical
Full Product Name
PF-06263276
Product Synonym Names
PF 06263276; PF06263276; PF 6263276
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
566.64
Target
JAK
Receptor
JAK
Chemical Name
(2-(6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl)-3, 4, 6, 7-tetrahydro-5H-imidazo[4, 5-c]pyridin-5-yl)(5-(piperidin-1-yl)pyrazin-2-yl)methanone
SMILES
FC1=C(O)C=C(CC)C(C2=CC(NN=C3C4=NC5=C(CN(C(C6=NC=C(N7CCCCC7)N=C6)=O)CC5)N4)=C3C=C2)=C1
Molecular Formula
C31H31FN8O2
CAS Number
1421502-62-6

Product References and Citations for PF-06263276 biochemical

1. Jones P, et al. J Med Chem. 2017 Jan 26; 60 (2):767-786.

Other Notes

Small volumes of PF-06263276 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-06263276 purchase

MBS3601766 is a biochemical targeting PF-06263276.
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