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Procainamide (Biocoryl)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5803052

Procainamide (Novocainamide) is a specific and potent DNA methyltransferase 1 (DNMT1) Inhibitor. Procainamide is a Class 1A antiarrhythmic agent. Procainamide has the potential for the research of cancer and arrhythmias. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Procainamide, Biochemical
Full Product Name
Procainamide
Product Synonym Names
Biocoryl; Novocainamide
Purity/Purification
98.86%
Preparation and Storage
Powder: -20 degree C for 3 years | In solvent: -80 degree C for 1 year
Molecular Weight
235.33
SMILES
C(NCCN(CC)CC)(=O)C1=CC=C(N)C=C1
Formula
C13H21N3O
Solubility
DMSO: 45mg/mL (191.2mM)
Need ultrasonic
(< 1 mg/ml refers to the product slightly soluble or insoluble)
CAS Number
51-06-9
In_vitro
HCT116, HCT116 DNMT1-/-, and HCT116 DNMT3b-/-cells were treated with PBS, pH 7.4 or 0.5 mM procainamide for 96 h. Procainamide treatment of HCT116 DNMT3b-/-cells decreased m5dC content by 11.5%, but treatment of HCT116 DNMT1-/-cells did not decrease m5dC content. These results suggested that DNMT1 was the intracellular target of procainamide[1].

Other Notes

Small volumes of Procainamide biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Procainamide purchase

MBS5803052 is a biochemical targeting Procainamide.
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