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RAF-709

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602436

A novel potent, selective, and orally bioavailable RAF inhibitor with biochemical IC50 of 0.4 nM and 0.5 nM for BRAF and CRAF, respectively. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RAF-709, Biochemical
Full Product Name
RAF-709
Product Synonym Names
RAF709; RAF 709
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
542.5495
Suitability
DMSO: 100mg/mL
Target
Raf
Receptor
B-Raf; C-Raf
Chemical Name
Benzamide, N-[2-methyl-5'-(4-morpholinyl)-6'-[(tetrahydro-2H-pyran-4-yl)oxy][3, 3'-bipyridin]-5-yl]-3-(trifluoromethyl)
SMILES
CC1=C(C=C(C=N1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)C3=CC(=C(N=C3)OC4CCOCC4)N5CCOCC5
Molecular Formula
C28H29F3N4O4
CAS Number
1628838-42-5

Product Categories/Family for RAF-709 biochemical

MAPK/ERK Signaling; Cancer

Structure of RAF-709 biochemical

RAF-709 Biochemical – Cat# MBS3602436

Product References and Citations for RAF-709 biochemical

1. Nishiguchi GA, et al. J Med Chem. 2017 Jun 22; 60 (12):4869-4881.

Other Notes

Small volumes of RAF-709 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAF-709 purchase

MBS3602436 is a biochemical targeting RAF-709.
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