Salinomycin (AHR 3096)

Name: Salinomycin (AHR 3096); MyBioSource
Brand: MyBioSource
SKU: MBS3604876
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604876

Salinomycin is an inhibitor of Wnt/beta-catenin signaling, which acts on the Wnt/Fzd/LRP complex. More details

$235 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Salinomycin, Biochemical

Full Product Name

Salinomycin

Product Synonym Names

AHR 3096; AHR3096; AHR-3096; K 364; Salinomycin; BioCox; Sacox; Salocin; Coxistac

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

751

Suitability

DMSO: >=36.7mg/mL

Target

Wnt/beta/catenin

Receptor

IC50: 163nM (Wnt1-stimulated reporter)

Chemical Name

(R)-2-((2R, 5S, 6R)-6-((2S, 3S, 4S, 6R)-6-((2S, 5S, 7R, 9S, 10S, 12R, 15R)-2-((2R, 5R, 6S)-5-ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)-15-hydroxy-2, 10, 12-trimethyl-1, 6, 8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl)-3-hydroxy-4-methyl-5-oxooctan-2-yl)-5-methyltetrahydro-2H-pyran-2-yl)butanoic acid

SMILES

CC[C@@H](C(O)=O)[C@H]1CC[C@@H]([C@H]([C@H]([C@@H]([C@@H](C([C@@H]([C@H]2O[C@]3([C@@H](C[C@@H]2C)C)O[C@]4([C@@H](C=C3)O)CC[C@](O4)([C@H]5CC[C@](CC)([C@@H](O5)C)O)C)CC)=O)C)O)C)O1)C

Molecular Formula

C??H??O??

CAS Number

53003-10-4

Product Categories/Family for Salinomycin biochemical

Wnt/Notch/Hedgehog; Infection

Product References and Citations for Salinomycin biochemical

1. Lu D, et al. Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells. Proc natl Acad Sci U S A. 2011 Aug 9; 108 (32):13253-7.
2. Zhou J, et al. Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactiveoxygen species. Toxicol Lett. 2013 Oct 24; 222 (2):139-45.

Other Notes

Small volumes of Salinomycin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Salinomycin purchase

MBS3604876 is a biochemical targeting Salinomycin.