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SG3199

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602278

SG3199 (SG-3199) is a PBD dimer warhead component of antibody-drug conjugate (ADC) payload tesirine, demonstrates potently cytotoxic against a panel of human solid tumour and haematological cancer cell lines with mean GI50 of 151.5 pM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SG3199, Biochemical
Full Product Name
SG3199
Product Synonym Names
SG-3199; SG 3199
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
584.673
Target
ADC Cytotoxin
Receptor
ADC Cytotoxin
Chemical Name
7-methoxy-8-((5-(((S)-7-methoxy-2-methyl-5-oxo-5, 11a-dihydro-1H-benzo[e]pyrrolo[1, 2-a][1, 4]diazepin-8-yl)oxy)pentyl)oxy)-2-methyl-1, 11a-dihydro-5H-benzo[e]pyrrolo[1, 2-a][1, 4]diazepin-5-one
SMILES
O=C1C2=CC(OC)=C(OCCCCCOC3=C(OC)C=C4C(N=C[C@@](CC(C)=C5)([H])N5C4=O)=C3)C=C2N=C[C@@]6([H])N1C=C(C)C6
Molecular Formula
C33H36N4O6
CAS Number
1595275-71-0

Product Categories/Family for SG3199 biochemical

Antibody Drug Conjugates (ADC)

Structure of SG3199 biochemical

SG3199 Biochemical – Cat# MBS3602278

Product References and Citations for SG3199 biochemical

1. Zammarchi F, et al. Blood. 2018 Mar 8; 131 (10):1094-1105.
2. Hartley JA, et al. Sci Rep. 2018 Jul 11; 8 (1):10479.

Other Notes

Small volumes of SG3199 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SG3199 purchase

MBS3602278 is a biochemical targeting SG3199.
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