TML-6

Name: TML-6; MyBioSource
Brand: MyBioSource
SKU: MBS5798113
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5798113

TML-6, an orally active curcumin derivative, inhibits the synthesis of the beta-amyloid precursor protein and beta-amyloid (Abeta). TML-6 can upregulate Apo E, suppress NF-kappaB and mTOR, and increase the activity of the anti-oxidative Nrf2 gene. TML-6 has… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TML-6, Biochemical

Full Product Name

TML-6

Product Gene Name

TML-6 biochemical

Purity/Purification

98%

Preparation and Storage

Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years

Formula

C30H37NO7

CAS

1462868-88-7

Solubility

DMSO: 120 mg/mL (229.17 mM),
Need ultrasonic
<1mg/ml refers to the product slightly soluble or insoluble

In vitro

TML-6 (diet; 150 mg/kg/day; for four months) treatment results in significant improvement in learning, suppression of the microglial activation marker Iba-1, and reduction in Abeta in the brain[1]. TML-6 (oral; 150 mg/kg) has a T1/2 of 1.27 hours, a Cmax of 35.9 ng/mL and an AUC of 177 ng/hr/mL[1].

Other Notes

Small volumes of TML-6 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TML-6 purchase

MBS5798113 is a biochemical targeting TML-6.

TML-6

Product Overview

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