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TRV055

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5800502

TRV055 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV055 is efficacious in stimulating cellular Gq-mediated signaling. TRV055 can be used to develop the Gq-biased AT1R agonists. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRV055, Biochemical
Full Product Name
TRV055
Purity/Purification
98%
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
CAS
25849-90-5
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
TRV055 is a "gain-of-function" ligand that have 10-fold greater allosteric coupling to Gq than AngII and is also more efficacious in stimulating cellular Gq-mediated signaling (e.g., IP1 generation). Compared to the endogenous ligand angiotensin II (AngII), "Gq-biased" AT1R agonists are more efficacious in stimulating Gq-mediated cellular signaling and in allosterically promoting Gq coupling[1].

Structure of TRV055 biochemical

Chrysophanol-1-O-beta-gentiobioside, CAS 54944-38-6
TRV055 Biochemical – Cat# MBS5800502

Structure of TRV055 biochemical

Chrysophanol-1-O-beta-gentiobioside, CAS 54944-38-6
TRV055 Biochemical, Structure – Cat# MBS5800502

Product References and Citations for TRV055 biochemical

1. Paudel P, et al. In Vitro and in Silico Human Monoamine Oxidase Inhibitory Potential of Anthraquinones, Naphthopyrones, and Naphthalenic Lactones from Cassia obtusifolia Linn Seeds. ACS Omega. 2019;4(14):16139-16152. Published 2019 Sep 18.

Other Notes

Small volumes of TRV055 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRV055 purchase

MBS5800502 is a biochemical targeting TRV055.
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