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Mouse Aak1 Antibody (Center) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9220937

Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Isoform 1 and isoform 2… More details

$455 / 0.5 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
Aak1, Blocking Peptide
Full Product Name
Mouse Aak1 Antibody (Center) Blocking Peptide
Product Gene Name
Product Synonym Gene Name
Kiaa1048
Product Synonym Names
AP2-associated protein kinase 1; Adaptor-associated kinase 1; Aak1; Kiaa1048
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
Aak1 peptide (MBS9220937) is used for blocking the activity of Aak1 antibody (MBS9214771)
Molecular Weight
94,661 Da
Cellular Location
Cell membrane; Peripheral membrane protein. Membrane, clathrin-coated pit. Note: Active when found in clathrin-coated pits at the plasma membrane. In neuronal cells, enriched at presynaptic terminals. In non-neuronal cells, enriched at leading edge of migrating cells (By similarity).

Other Notes

Small volumes of Aak1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Aak1 purchase

MBS9220937 is a blocking peptide targeting Aak1. Also known as Mouse Aak1 Antibody (Center) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for Aak1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
AP2-associated protein kinase 1
NCBI Official Synonym Full Names
AP2 associated kinase 1
NCBI Official Symbol
Aak1
NCBI Official Synonym Symbols
C79663; R75501; AU067724; AU067726; BC028270; mKIAA1048; 9630042K20; D6Ertd245e; 5530400K14Rik
UniProt Protein Name
AP2-associated protein kinase 1
UniProt Synonym Protein Names
Adaptor-associated kinase 1
UniProt Gene Name
Aak1
UniProt Synonym Gene Names
Kiaa1048
UniProt Entry Name
AAK1_MOUSE
NCBI Protein Information
AP2 associated kinase 1

UniProt Comments for Aak1

AAK1: an NAK kinase. Plays a regulatory role in clathrin-mediated endocytosis, including the regulation of fatty acid synthesis and cholesterol synthesis.

Protein type: Protein kinase, Other; EC 2.7.11.1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Other group; NAK family

Cellular Component: cytoplasm; leading edge; terminal button

Molecular Function: Notch binding; protein serine/threonine kinase activity

Biological Process: positive regulation of Notch signaling pathway; protein amino acid autophosphorylation; protein amino acid phosphorylation; protein stabilization; regulation of protein localization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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