ACADL Blocking Peptide – Cat# MBS9621510

ACADL Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: ACADL Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9621510
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9621510

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ACADL, Blocking Peptide

Full Product Name

ACADL Blocking Peptide

Product Gene Name

ACADL blocking peptide

Product Synonym Names

ACAD4; ACADL; ACADL_HUMAN; Acyl Coenzyme A dehydrogenase long chain; Acyl-CoA dehydrogenase long chain; FLJ94052; LCAD; Long chain acyl CoA dehydrogenase; Long-chain specific acyl-CoA dehydrogenase, mitochondrial

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

ACADL peptide (MBS9621510) is used for blocking the activity of ACADL antibody (MBS9611557)

Molecular Weight

430

OMIM

phenotype 609576

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for ACADL blocking peptide

Blocking/Control

Other Notes

Small volumes of ACADL blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ACADL purchase

MBS9621510 is a blocking peptide targeting ACADL.

Additional Details

NCBI/Uniprot data below describe general gene information for ACADL. It may not necessarily be applicable to this product.

NCBI GI #

223590148

NCBI GeneID

NCBI Accession #

P28330.2

UniProt Primary Accession #

P28330

UniProt Secondary Accession #

Q8IUN8; B2R8T3

UniProt Related Accession #

P28330

NCBI Official Full Name

Long-chain specific acyl-CoA dehydrogenase, mitochondrial

NCBI Official Synonym Full Names

acyl-CoA dehydrogenase, long chain

NCBI Official Symbol

ACADL

NCBI Official Synonym Symbols

LCAD; ACAD4

UniProt Protein Name

Long-chain specific acyl-CoA dehydrogenase, mitochondrial

Protein Family

Long-chain specific acyl-CoA dehydrogenase

UniProt Gene Name

ACADL

UniProt Synonym Gene Names

LCAD

UniProt Entry Name

ACADL_HUMAN

NCBI Protein Information

long-chain specific acyl-CoA dehydrogenase, mitochondrial; acyl-Coenzyme A dehydrogenase, long chain

NCBI Summary for ACADL

The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008]

UniProt Comments for ACADL

ACADL: Defects in ACADL are a cause of acyl-CoA dehydrogenase very long-chain deficiency (ACADVLD). An inborn error of mitochondrial fatty acid beta-oxidation which leads to impaired long-chain fatty acid beta-oxidation. It is clinically heterogeneous, with three major phenotypes: a severe childhood form characterized by early onset, high mortality and high incidence of cardiomyopathy; a milder childhood form with later onset, characterized by hypoketotic hypoglycemia, low mortality and rare cardiomyopathy; an adult form, with isolated skeletal muscle involvement, rhabdomyolysis and myoglobinuria, usually triggered by exercise or fasting. Belongs to the acyl-CoA dehydrogenase family.

Protein type: Mitochondrial; Lipid Metabolism - fatty acid; EC 1.3.8.8; Oxidoreductase

Chromosomal Location of Human Ortholog: 2q34

Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial membrane; cytoplasm

Molecular Function: palmitoyl-CoA oxidase activity; acyl-CoA dehydrogenase activity; FAD binding; acyl-CoA binding; long-chain-acyl-CoA dehydrogenase activity

Biological Process: carnitine metabolic process, CoA-linked; fatty acid beta-oxidation; cellular lipid catabolic process; carnitine catabolic process; thermoregulation; cellular lipid metabolic process; fatty acid beta-oxidation using acyl-CoA dehydrogenase; negative regulation of fatty acid oxidation; negative regulation of fatty acid biosynthetic process; long-chain fatty acid catabolic process; protein homotetramerization

Research Articles on ACADL

1. the fatty acid oxidation pathway and LCAD are factors contributing to the pathophysiology of pulmonary disease

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ACADL blocking peptide

Reference Product	PubMed Publications
ACADM blocking peptide	>7 publications with ACADL and ACADM
CPT1B blocking peptide	>4 publications with ACADL and CPT1B
CPT1A blocking peptide	>2 publications with ACADL and CPT1A
EHHADH blocking peptide	>2 publications with ACADL and EHHADH
HADHA blocking peptide	>1 publications with ACADL and HADHA
ACAA2 blocking peptide	>1 publications with ACADL and ACAA2
HADHB blocking peptide	>1 publications with ACADL and HADHB

Pathways associated with ACADL blocking peptide

Products by Pathway	Pathway Diagram
Beta Oxidation Of Lauroyl-CoA To Decanoyl-CoA-CoA Pathway antibodies	Beta Oxidation Of Lauroyl-CoA To Decanoyl-CoA-CoA Pathway Diagram
Beta Oxidation Of Myristoyl-CoA To Lauroyl-CoA Pathway antibodies	Beta Oxidation Of Myristoyl-CoA To Lauroyl-CoA Pathway Diagram
Fatty Acid Beta Oxidation Pathway antibodies	Fatty Acid Beta Oxidation Pathway Diagram
Fatty Acid Degradation Pathway antibodies	Fatty Acid Degradation Pathway Diagram
Fatty Acid Degradation Pathway antibodies	Fatty Acid Degradation Pathway Diagram
Fatty Acid Metabolism Pathway antibodies	Fatty Acid Metabolism Pathway Diagram
Fatty Acid Metabolism Pathway antibodies	Fatty Acid Metabolism Pathway Diagram
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies	Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram

Diseases associated with ACADL blocking peptide

Disease Name	Pubmed Publications
Fatty Liver Antibodies	>10 publications with ACADL and Fatty Liver
Liver Diseases Antibodies	>8 publications with ACADL and Liver Diseases
Weight Gain Antibodies	>2 publications with ACADL and Weight Gain
Learning Disorders Antibodies	>1 publications with ACADL and Learning Disorders
Nervous System Diseases Antibodies	>1 publications with ACADL and Nervous System Diseases
Cardiovascular Diseases Antibodies	>1 publications with ACADL and Cardiovascular Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with ACADL and Carcinoma, Hepatocellular
Inflammation Antibodies	>1 publications with ACADL and Inflammation
Hepatomegaly Antibodies	>1 publications with ACADL and Hepatomegaly
Liver Neoplasms Antibodies	>1 publications with ACADL and Liver Neoplasms

Organs/Tissues associated with ACADL blocking peptide

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>12 publications with ACADL and Liver
Connective Tissue Antibodies	>6 publications with ACADL and Connective Tissue
Muscle Antibodies	>5 publications with ACADL and Muscle
Pancreas Antibodies	>4 publications with ACADL and Pancreas
Prostate Antibodies	>2 publications with ACADL and Prostate
Bone Antibodies	>1 publications with ACADL and Bone