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ALOX15 Peptide - Middle Region Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3237481

This is a synthetic peptide designed for use in combination with anti-ALOX15 antibody madeTarget Description: ALOX15 converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. ALOX15 also acts on C-12 of arachidonate as well as on linoleic acid. More details

$195 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ALOX15, Blocking Peptide
Full Product Name
ALOX15 Peptide - middle region
Product Gene Name
ALOX15 blocking peptide
Product Synonym Gene Name
15-LOX2; 15LOX-1; 15-LOX-1
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Antibody/Peptide Pairs
ALOX15 peptide (MBS3237481) is used for blocking the activity of ALOX15 antibody (MBS3212534)
Molecular Weight
73kDa
OMIM
152392

Product Categories/Family for ALOX15 blocking peptide

Peptide
Applications Tested/Suitable for ALOX15 blocking peptide
Western Blot (WB)

Other Notes

Small volumes of ALOX15 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALOX15 purchase

MBS3237481 is a blocking peptide targeting ALOX15. Also known as ALOX15 Peptide - middle region.

Additional Details

NCBI/Uniprot data below describe general gene information for ALOX15. It may not necessarily be applicable to this product.

NCBI GI #
40316937
NCBI GeneID
246
NCBI Accession #
NP_001131
UniProt Primary Accession #
P16050
UniProt Related Accession #
P16050
GenBank Nucleotide #
NM_001140
NCBI Official Full Name
arachidonate 15-lipoxygenase
NCBI Official Synonym Full Names
arachidonate 15-lipoxygenase
NCBI Official Symbol
ALOX15
NCBI Official Synonym Symbols
LOG15; 12-LOX; 15-LOX; 15-LOX-1
UniProt Protein Name
Arachidonate 15-lipoxygenase
UniProt Synonym Protein Names
Arachidonate omega-6 lipoxygenase
UniProt Gene Name
ALOX15
UniProt Synonym Gene Names
LOG15; 15-LOX
UniProt Entry Name
LOX15_HUMAN
NCBI Protein Information
arachidonate 15-lipoxygenase

NCBI Summary for ALOX15

This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on various polyunsaturated fatty acid substrates to generate various bioactive lipid mediators such as eicosanoids, hepoxilins, lipoxins, and other molecules. The encoded enzyme and its reaction products have been shown to regulate inflammation and immunity. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]
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UniProt Comments for ALOX15

ALOX15: Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Belongs to the lipoxygenase family.

Protein type: Lipid Metabolism - linoleic acid; EC 1.13.11.33; EC 1.13.11.31; Oxidoreductase; Lipid Metabolism - arachidonic acid; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: extrinsic to internal side of plasma membrane; membrane; plasma membrane; lipid particle; cytosol

Molecular Function: protein binding; phosphatidylinositol-4,5-bisphosphate binding; hepoxilin A3 synthase activity; arachidonate 12-lipoxygenase activity; arachidonate 15-lipoxygenase activity; hepoxilin-epoxide hydrolase activity; iron ion binding

Biological Process: ossification; positive regulation of heterotypic cell-cell adhesion; positive regulation of actin filament polymerization; wound healing; lipoxygenase pathway; negative regulation of adaptive immune response; phosphatidylethanolamine biosynthetic process; arachidonic acid metabolic process; leukotriene metabolic process; hepoxilin biosynthetic process; inflammatory response; apoptotic cell clearance; bone mineralization
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Research Articles on ALOX15

1. Results demonstrate the expression of ALOX15 and ALOX15B in failing as well as in donor hearts. ALOX15/B signaling may play an important role in heart disease, including heart failure. Isolated fibroblasts from all four chambers of the heart expressed ALOX15 as well as ALOX15B, and gene expression levels were further increased under hypoxia.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ALOX15 blocking peptide

 Reference Product  PubMed Publications
 ALOX5 blocking peptide  >217 publications with ALOX15 and ALOX5
 PTGS2 blocking peptide  >53 publications with ALOX15 and PTGS2
 ALOX15B blocking peptide  >51 publications with ALOX15 and ALOX15B
 PTGS1 blocking peptide  >27 publications with ALOX15 and PTGS1
 PLA2G4A blocking peptide  >18 publications with ALOX15 and PLA2G4A
 STAT6 blocking peptide  >12 publications with ALOX15 and STAT6
 ALOX12B blocking peptide  >4 publications with ALOX15 and ALOX12B
 CYP2J2 blocking peptide  >2 publications with ALOX15 and CYP2J2

Pathways associated with ALOX15 blocking peptide

 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Eicosanoid Synthesis Pathway antibodies  Eicosanoid Synthesis Pathway Diagram
 IL4-mediated Signaling Events Pathway antibodies  IL4-mediated Signaling Events Pathway Diagram
 Linoleic Acid Metabolism Pathway antibodies  Linoleic Acid Metabolism Pathway Diagram
 Linoleic Acid Metabolism Pathway antibodies  Linoleic Acid Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram

Diseases associated with ALOX15 blocking peptide

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >214 publications with ALOX15 and Inflammation
 Atherosclerosis Antibodies  >138 publications with ALOX15 and Atherosclerosis
 Disease Models, Animal Antibodies  >68 publications with ALOX15 and Disease Models, Animal
 Hypertension Antibodies  >37 publications with ALOX15 and Hypertension
 Necrosis Antibodies  >28 publications with ALOX15 and Necrosis
 Kidney Diseases Antibodies  >23 publications with ALOX15 and Kidney Diseases
 Heart Diseases Antibodies  >20 publications with ALOX15 and Heart Diseases
 Fibrosis Antibodies  >16 publications with ALOX15 and Fibrosis
 Arthritis, Rheumatoid Antibodies  >14 publications with ALOX15 and Arthritis, Rheumatoid
 Pain Antibodies  >11 publications with ALOX15 and Pain

Organs/Tissues associated with ALOX15 blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >105 publications with ALOX15 and Lung
 Prostate Antibodies  >46 publications with ALOX15 and Prostate
 Trachea Antibodies  >17 publications with ALOX15 and Trachea
 Intestine Antibodies  >16 publications with ALOX15 and Intestine
 Embryonic Tissue Antibodies  >12 publications with ALOX15 and Embryonic Tissue
 Adipose Tissue Antibodies  >11 publications with ALOX15 and Adipose Tissue
 Placenta Antibodies  >11 publications with ALOX15 and Placenta
 Lymph Node Antibodies  >6 publications with ALOX15 and Lymph Node
 Testis Antibodies  >3 publications with ALOX15 and Testis
 Mouth Antibodies  >3 publications with ALOX15 and Mouth
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