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APOB48R Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9620483

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
APOB48R, Blocking Peptide
Full Product Name
APOB48R Blocking Peptide
Product Gene Name
APOB48R blocking peptide
Product Synonym Gene Name
APOBR
Product Synonym Names
apo b-100; APOB; apoB-48R; APOBR; APOBR_HUMAN; Apolipoprotein B receptor; Apolipoprotein B-100 receptor; Apolipoprotein B-48 receptor; Apolipoprotein B48 receptor
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.
Purity/Purification
The purity is >90%,tested by HPLC and MS.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
APOB48R peptide (MBS9620483) is used for blocking the activity of APOB48R antibody (MBS9603006)
Molecular Weight
Predicted MW: 14.7 kDa
Observed MW: 17 kDa
(The reducing (R) protein migrates as xx kDa in SDS-PAGE may be due to relative charge.)
OMIM
605220
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Notes
For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for APOB48R blocking peptide
Blocking/Control

Other Notes

Small volumes of APOB48R blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APOB48R purchase

MBS9620483 is a blocking peptide targeting APOB48R.

Additional Details

NCBI/Uniprot data below describe general gene information for APOB48R. It may not necessarily be applicable to this product.

NCBI GI #
340138932
NCBI GeneID
55911
NCBI Accession #
NP_061160.3
UniProt Primary Accession #
Q0VD83
UniProt Secondary Accession #
Q0VD81; Q8NC15; Q9NPJ9; H3BU97
UniProt Related Accession #
Q0VD83
GenBank Nucleotide #
NM_018690.3
NCBI Official Full Name
apolipoprotein B receptor
NCBI Official Synonym Full Names
apolipoprotein B receptor
NCBI Official Symbol
APOBR
NCBI Official Synonym Symbols
APOB48R; APOB100R
UniProt Protein Name
Apolipoprotein B receptor
UniProt Synonym Protein Names
Apolipoprotein B-100 receptor; Apolipoprotein B-48 receptor
UniProt Gene Name
APOBR
UniProt Synonym Gene Names
APOB48R; Apolipoprotein B48 receptor; apoB-48R
UniProt Entry Name
APOBR_HUMAN
NCBI Protein Information
apolipoprotein B receptor

NCBI Summary for APOB48R

Apolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG)-rich lipoproteins. This receptor may provide essential lipids, lipid-soluble vitamins and other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis. [provided by RefSeq, Jul 2008]
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UniProt Comments for APOB48R

APOB48R: Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG- VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.

Chromosomal Location of Human Ortholog: 16p11

Cellular Component: chylomicron; membrane; plasma membrane

Molecular Function: very-low-density lipoprotein receptor activity

Biological Process: receptor-mediated endocytosis; cholesterol metabolic process; triacylglycerol metabolic process; lipid transport
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Research Articles on APOB48R

1. The obesity risk alleles of non-synonymous SNPs at SH2B1 and APOB48R have no strong effect on weight loss-related phenotypes in overweight children after a 1-year lifestyle intervention.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with APOB48R blocking peptide

 Reference Product  PubMed Publications
 CLN3 blocking peptide  >1 publications with APOB48R and CLN3

Pathways associated with APOB48R blocking peptide

 Products by Pathway  Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Lipoprotein Metabolism Pathway antibodies  Lipoprotein Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 VLDL Interactions Pathway antibodies  VLDL Interactions Pathway Diagram

Organs/Tissues associated with APOB48R blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with APOB48R and Blood
 Connective Tissue Antibodies  >1 publications with APOB48R and Connective Tissue
 Brain Antibodies  >1 publications with APOB48R and Brain
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