• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

BIN2 Antibody (N-Term) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9225780

Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome… More details

$455 / 0.5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BIN2, Blocking Peptide
Full Product Name
BIN2 Antibody (N-term) Blocking peptide
Product Gene Name
Product Synonym Gene Name
BRAP1
Product Synonym Names
Bridging integrator 2; Breast cancer-associated protein 1; BIN2; BRAP1
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
BIN2 peptide (MBS9225780) is used for blocking the activity of BIN2 antibody (MBS9206689)
Molecular Weight
58,030 Da
OMIM
605936
Cellular Location
Cytoplasm. Cell projection, podosome membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasm, cell cortex. Cell projection, phagocytic cup Note: Associates with membranes enriched in phosphoinositides Detected in the actin-rich cell cortex at the leading edge of migrating cells. Detected at podosomes, at an actin-rich ring-like structure
Tissue Location
Detected in natural killer cells (at protein level). Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues.

Other Notes

Small volumes of BIN2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BIN2 purchase

MBS9225780 is a blocking peptide targeting BIN2. Also known as BIN2 Antibody (N-term) Blocking peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for BIN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
bridging integrator 2
NCBI Official Synonym Full Names
bridging integrator 2
NCBI Official Symbol
BIN2
NCBI Official Synonym Symbols
BRAP-1
UniProt Protein Name
Bridging integrator 2
UniProt Synonym Protein Names
Breast cancer-associated protein 1
Protein Family
UniProt Gene Name
BIN2
UniProt Synonym Gene Names
BRAP1
UniProt Entry Name
BIN2_HUMAN
NCBI Protein Information
bridging integrator 2

UniProt Comments for BIN2

BIN2: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: phagocytic cup; podosome

Molecular Function: phospholipid binding; protein binding

Biological Process: phagocytosis, engulfment

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000