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BLVRB Blocking Peptide (Center) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9228781

Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
BLVRB, Blocking Peptide
Full Product Name
BLVRB Blocking Peptide (Center)
Product Gene Name
Product Synonym Gene Name
FLR
Product Synonym Names
Flavin reductase (NADPH); FR; Biliverdin reductase B; BVR-B; Biliverdin-IX beta-reductase; Green heme-binding protein; GHBP; NADPH-dependent diaphorase; NADPH-flavin reductase; FLR; BLVRB; FLR
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Specificity
The synthetic peptide sequence is selected from aa 134-146 of HUMAN BLVRB
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
BLVRB peptide (MBS9228781) is used for blocking the activity of BLVRB antibody (MBS9213980)
Molecular Weight
22,119 Da
OMIM
600941
Cellular Location
Cytoplasm.
Tissue Location
Predominantly expressed in liver and erythrocytes. At lower levels in heart, lung, adrenal gland and cerebrum.

Other Notes

Small volumes of BLVRB blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BLVRB purchase

MBS9228781 is a blocking peptide targeting BLVRB. Also known as BLVRB Blocking Peptide (Center).

Additional Details

NCBI/Uniprot data below describe general gene information for BLVRB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
flavin reductase (NADPH)
NCBI Official Synonym Full Names
biliverdin reductase B
NCBI Official Symbol
BLVRB
NCBI Official Synonym Symbols
FLR; BVRB; SDR43U1; HEL-S-10
UniProt Protein Name
Flavin reductase (NADPH)
UniProt Synonym Protein Names
Biliverdin reductase B (EC:1.3.1.24
UniProt Gene Name
BLVRB
UniProt Synonym Gene Names
FLR; BVR-B; GHBP; FLR
UniProt Entry Name
BLVRB_HUMAN
NCBI Protein Information
flavin reductase (NADPH)

NCBI Summary for BLVRB

The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24).[supplied by OMIM, Jul 2009]

UniProt Comments for BLVRB

BLVRB: Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.

Protein type: EC 1.3.1.24; Oxidoreductase; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; EC 1.5.1.30

Chromosomal Location of Human Ortholog: 19q13.1-q13.2

Cellular Component: cytoplasm; cytosol; nucleoplasm; plasma membrane

Molecular Function: biliverdin reductase activity; flavin reductase activity

Biological Process: heme catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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