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CENPO Antibody (N-Term) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9222932

Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into… More details

$455 / 0.5 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CENPO, Blocking Peptide
Full Product Name
CENPO Antibody (N-term) Blocking Peptide
Product Gene Name
Product Synonym Gene Name
ICEN36; MCM21R
Product Synonym Names
Centromere protein O; CENP-O; Interphase centromere complex protein 36; CENPO; ICEN36; MCM21R
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
CENPO peptide (MBS9222932) is used for blocking the activity of CENPO antibody (MBS9201182)
Molecular Weight
32,989 Da
OMIM
611504
Cellular Location
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note: The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex

Other Notes

Small volumes of CENPO blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CENPO purchase

MBS9222932 is a blocking peptide targeting CENPO. Also known as CENPO Antibody (N-term) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for CENPO. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Centromere protein O
NCBI Official Synonym Full Names
centromere protein O
NCBI Official Symbol
CENPO
NCBI Official Synonym Symbols
CENP-O; MCM21R; ICEN-36
UniProt Protein Name
Centromere protein O
UniProt Synonym Protein Names
Interphase centromere complex protein 36
Protein Family
UniProt Gene Name
CENPO
UniProt Synonym Gene Names
ICEN36; MCM21R; CENP-O
UniProt Entry Name
CENPO_HUMAN
NCBI Protein Information
centromere protein O

NCBI Summary for CENPO

This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
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UniProt Comments for CENPO

CENPO: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: cytosol; nucleoplasm

Molecular Function: protein binding

Biological Process: DNA replication-independent nucleosome assembly at centromere; sister chromatid cohesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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