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CHSY3 Blocking Peptide (C-Term) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9229988

Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer.… More details

$455 / 0.5 mg +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CHSY3, Blocking Peptide
Full Product Name
CHSY3 Blocking Peptide (C-term)
Product Gene Name
CHSY3 blocking peptide
Product Synonym Gene Name
CHSY2; CSS3
Product Synonym Names
Chondroitin sulfate synthase 3; Carbohydrate synthase 2; Chondroitin glucuronyltransferase 3; Chondroitin synthase 2; ChSy-2; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3; N-acetylgalactosaminyltransferase 3; CHSY3; CHSY2; CSS3
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Specificity
The synthetic peptide sequence is selected from aa 751-765 of HUMAN CHSY3
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
CHSY3 peptide (MBS9229988) is used for blocking the activity of CHSY3 antibody (MBS9214460)
Molecular Weight
100,284 Da
OMIM
609963
Cellular Location
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein
Tissue Location
Detected at low levels in brain, cerebral cortex, uterus and small intestine.

Other Notes

Small volumes of CHSY3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CHSY3 purchase

MBS9229988 is a blocking peptide targeting CHSY3. Also known as CHSY3 Blocking Peptide (C-term).

Additional Details

NCBI/Uniprot data below describe general gene information for CHSY3. It may not necessarily be applicable to this product.

NCBI GI #
145559453
NCBI GeneID
337876
NCBI Accession #
Q70JA7.3
UniProt Primary Accession #
Q70JA7
UniProt Secondary Accession #
Q76L22; Q86Y52; B2RP97
UniProt Related Accession #
Q70JA7
NCBI Official Full Name
Chondroitin sulfate synthase 3
NCBI Official Synonym Full Names
chondroitin sulfate synthase 3
NCBI Official Symbol
CHSY3
NCBI Official Synonym Symbols
CSS3; CHSY2
UniProt Protein Name
Chondroitin sulfate synthase 3
UniProt Synonym Protein Names
Carbohydrate synthase 2; Chondroitin glucuronyltransferase 3; Chondroitin synthase 2; ChSy-2; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3; N-acetylgalactosaminyltransferase 3
Protein Family
Chondroitin sulfate synthase
UniProt Gene Name
CHSY3
UniProt Synonym Gene Names
CHSY2; CSS3; ChSy-2
UniProt Entry Name
CHSS3_HUMAN
NCBI Protein Information
chondroitin sulfate synthase 3

NCBI Summary for CHSY3

CSS3 is a glycosyltransferase that has both glucuronyltransferase and N-acetylgalactosaminyltransferase activities (Yada et al., 2003 [PubMed 12907687]).[supplied by OMIM, Mar 2008]

UniProt Comments for CHSY3

CSS3: Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1. Belongs to the chondroitin N- acetylgalactosaminyltransferase family.

Protein type: Membrane protein, integral; Transferase; Glycan Metabolism - chondroitin sulfate biosynthesis; EC 2.4.1.175; EC 2.4.1.226

Chromosomal Location of Human Ortholog: 5q23.3

Cellular Component: Golgi membrane

Molecular Function: glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity

Biological Process: chondroitin sulfate biosynthetic process
Show more

Research Articles on CHSY3

1. The present study focused on the expression of chondroitin-synthesizing enzymes in colorectal cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CHSY3 blocking peptide

 Products by Pathway  Pathway Diagram
 Chondroitin Sulfate Biosynthesis Pathway antibodies  Chondroitin Sulfate Biosynthesis Pathway Diagram
 Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies  Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram
 Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway Diagram
 Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway Diagram
 Glycosaminoglycan Biosynthesis, Chondroitin Sulfate Backbone Pathway antibodies  Glycosaminoglycan Biosynthesis, Chondroitin Sulfate Backbone Pathway Diagram
 Glycosaminoglycan Biosynthesis, Chondroitin Sulfate Backbone Pathway antibodies  Glycosaminoglycan Biosynthesis, Chondroitin Sulfate Backbone Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram

Diseases associated with CHSY3 blocking peptide

 Disease Name  Pubmed Publications
 Vascular Diseases Antibodies  >2 publications with CHSY3 and Vascular Diseases
 Cardiovascular Diseases Antibodies  >1 publications with CHSY3 and Cardiovascular Diseases

Organs/Tissues associated with CHSY3 blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with CHSY3 and Bone
 Vascular Antibodies  >1 publications with CHSY3 and Vascular
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