CYC1 Peptide - Middle Region Blocking Peptide

This gene encodes a subunit of the cytochrome bc1 complex, which plays an important role in the mitochondrial respiratory chain by transferring electrons from the Rieske iron-sulfur protein to cytochrome c. Mutations in this gene may cause mitochondrial complex III deficiency, nuclear type 6. [provided by RefSeq, Dec 2013]

CYC1: This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain. Belongs to the cytochrome c family.

Protein type: Mitochondrial; Energy Metabolism - oxidative phosphorylation; Membrane protein, integral; Oxidoreductase

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: membrane; mitochondrion; mitochondrial inner membrane; integral to membrane; nucleus

Molecular Function: electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity; iron ion binding; heme binding

Biological Process: cellular metabolic process; response to glucagon stimulus

Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 6