Dopamine D4 Receptor Antibody Antigenic Blocking Peptide

DRD4: Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Its activity is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1

Cellular Component: axon; cell cortex; cell soma; cytoplasm; dendrite; dendritic spine; integral to membrane; integral to plasma membrane; membrane; nerve terminal; plasma membrane; terminal button; vesicle membrane

Molecular Function: dopamine binding; dopamine D1 receptor-like receptor activity; dopamine D2 receptor-like receptor activity; dopamine receptor activity; drug binding; G-protein coupled receptor activity; identical protein binding; SH3 domain binding; signal transducer activity

Biological Process: activation of MAPK activity; adult locomotory behavior; arachidonic acid secretion; associative learning; behavioral fear response; behavioral response to cocaine; dopamine receptor signaling pathway; dopamine receptor, adenylate cyclase inhibiting pathway; fear response; G-protein coupled receptor protein signaling pathway; negative regulation of adenylate cyclase activity; negative regulation of cAMP biosynthetic process; negative regulation of protein secretion; olfactory learning; positive regulation of kinase activity; positive regulation of sodium:hydrogen antiporter activity; regulation of calcium-mediated signaling; regulation of circadian rhythm; regulation of dopamine metabolic process; regulation of inhibitory postsynaptic membrane potential; regulation of neurotransmitter secretion; regulation of synaptic transmission; response to amphetamine; rhythmic process; short-term memory; signal transduction; synaptic transmission, dopaminergic