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Eg5 Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9619556

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EG5, Blocking Peptide
Full Product Name
Eg5 Blocking Peptide
Product Gene Name
EG5 blocking peptide
Product Synonym Gene Name
KIF11
Product Synonym Names
EG5; HKSP; KIF11; KIF11_HUMAN; Kinesin family member 11; Kinesin like protein 1; Kinesin-like protein 1; Kinesin-like protein KIF11; Kinesin-like spindle protein HKSP; Kinesin-related motor protein Eg5; KNSL1; MCLMR; Thyroid receptor-interacting protein 5; TR-interacting protein 5; TRIP-5; TRIP5
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.
Purity/Purification
The purity is >90%,tested by HPLC and MS.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
Eg5 peptide (MBS9619556) is used for blocking the activity of Eg5 antibody (MBS9602101)
Molecular Weight
119,159 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (94352825..94415152). Location: 10q24.1
OMIM
148760
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Notes
For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for EG5 blocking peptide
Blocking/Control

Other Notes

Small volumes of EG5 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EG5 purchase

MBS9619556 is a blocking peptide targeting EG5.

Additional Details

NCBI/Uniprot data below describe general gene information for EG5. It may not necessarily be applicable to this product.

NCBI GI #
13699824
NCBI GeneID
3832
NCBI Accession #
NP_004514.2
UniProt Primary Accession #
P52732
UniProt Secondary Accession #
Q15716; Q5VWX0; A0AV49; B2RMV3
UniProt Related Accession #
P52732
GenBank Nucleotide #
NM_004523.3
NCBI Official Full Name
kinesin-like protein KIF11
NCBI Official Synonym Full Names
kinesin family member 11
NCBI Official Symbol
KIF11
NCBI Official Synonym Symbols
EG5; HKSP; KNSL1; MCLMR; TRIP5
UniProt Protein Name
Kinesin-like protein KIF11
UniProt Synonym Protein Names
Kinesin-like protein 1; Kinesin-like spindle protein HKSP; Kinesin-related motor protein Eg5; Thyroid receptor-interacting protein 5
Protein Family
Kinesin-like protein
UniProt Gene Name
KIF11
UniProt Synonym Gene Names
EG5; KNSL1; TRIP5; TR-interacting protein 5; TRIP-5
UniProt Entry Name
KIF11_HUMAN
NCBI Protein Information
kinesin-like protein KIF11; TRIP-5; kinesin-like protein 1; TR-interacting protein 5; kinesin-like spindle protein HKSP; kinesin-related motor protein Eg5; thyroid receptor-interacting protein 5

NCBI Summary for EG5

This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. [provided by RefSeq, Jul 2008]
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UniProt Comments for EG5

KIF11: a cytoskeletal protein that belongs to the kinesin-like protein family. BimC subfamily. Interacts with the thyroid hormone receptor in the presence of thyroid hormone. Plays a role in chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. Phosphorylation regulates its association with the spindle apparatus.

Protein type: Microtubule-binding; Motor

Chromosomal Location of Human Ortholog: 10q24.1

Cellular Component: spindle pole; kinesin complex; microtubule; membrane; spindle microtubule; cytoplasm; spindle; cytosol

Molecular Function: plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; protein complex binding; microtubule motor activity; protein kinase binding; ATP binding

Biological Process: mitosis; mitotic spindle organization and biogenesis; mitotic centrosome separation; cell division; metabolic process; regulation of mitotic centrosome separation; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; spindle organization and biogenesis; microtubule-based movement; chromosome segregation

Disease: Microcephaly With Or Without Chorioretinopathy, Lymphedema, Or Mental Retardation
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Research Articles on EG5

1. Eg5 directly interacts with NuMA in the vicinity of the spindle poles, although the interaction does not occur in interphase cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EG5 blocking peptide

 Reference Product  PubMed Publications
 CDK1 blocking peptide  >5 publications with EG5 and CDK1

Pathways associated with EG5 blocking peptide

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Kinesins Pathway antibodies  Kinesins Pathway Diagram
 MHC Class II Antigen Presentation Pathway antibodies  MHC Class II Antigen Presentation Pathway Diagram

Diseases associated with EG5 blocking peptide

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >60 publications with EG5 and Neoplasms
 Carcinoma Antibodies  >10 publications with EG5 and Carcinoma
 Nervous System Diseases Antibodies  >8 publications with EG5 and Nervous System Diseases
 Prostatic Neoplasms Antibodies  >7 publications with EG5 and Prostatic Neoplasms
 Breast Neoplasms Antibodies  >7 publications with EG5 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >7 publications with EG5 and Neoplasms, Experimental
 Aneuploidy Antibodies  >6 publications with EG5 and Aneuploidy
 Cardiovascular Diseases Antibodies  >5 publications with EG5 and Cardiovascular Diseases
 Ovarian Neoplasms Antibodies  >4 publications with EG5 and Ovarian Neoplasms
 Urinary Bladder Neoplasms Antibodies  >3 publications with EG5 and Urinary Bladder Neoplasms

Organs/Tissues associated with EG5 blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >15 publications with EG5 and Blood
 Brain Antibodies  >12 publications with EG5 and Brain
 Prostate Antibodies  >7 publications with EG5 and Prostate
 Lung Antibodies  >6 publications with EG5 and Lung
 Liver Antibodies  >4 publications with EG5 and Liver
 Bone Antibodies  >4 publications with EG5 and Bone
 Muscle Antibodies  >3 publications with EG5 and Muscle
 Skin Antibodies  >3 publications with EG5 and Skin
 Kidney Antibodies  >3 publications with EG5 and Kidney
 Heart Antibodies  >3 publications with EG5 and Heart
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