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Elf3 Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3225579

This is a synthetic peptide designed for use in combination with anti-ELF3 antibody madeTarget Description: ELF3 is a novel, highly tissue-restricted member of the ets transcription factor/oncogene family. ELF3 contains two putative DNA binding domains: an… More details

$195 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Elf3, Blocking Peptide
Full Product Name
Elf3 Peptide
Product Gene Name
Elf3 blocking peptide
Product Synonym Gene Name
EPR-1; ERT; ESE-1; ESX
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Antibody/Peptide Pairs
Elf3 peptide (MBS3225579) is used for blocking the activity of Elf3 antibody (MBS3200527)
Molecular Weight
41kDa
OMIM
602191

Product Categories/Family for Elf3 blocking peptide

Peptide
Applications Tested/Suitable for Elf3 blocking peptide
Western Blot (WB)

Other Notes

Small volumes of Elf3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Elf3 purchase

MBS3225579 is a blocking peptide targeting Elf3. Also known as Elf3 Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for Elf3. It may not necessarily be applicable to this product.

NCBI GI #
167235023
NCBI GeneID
1999
NCBI Accession #
NP_004424
UniProt Primary Accession #
P78545
UniProt Related Accession #
P78545
GenBank Nucleotide #
NM_004433
NCBI Official Full Name
ETS-related transcription factor Elf-3
NCBI Official Synonym Full Names
E74 like ETS transcription factor 3
NCBI Official Symbol
ELF3
NCBI Official Synonym Symbols
ERT; ESX; EPR-1; ESE-1
UniProt Protein Name
ETS-related transcription factor Elf-3
UniProt Synonym Protein Names
E74-like factor 3; Epithelial-restricted with serine box; Epithelium-restricted Ets protein ESX; Epithelium-specific Ets transcription factor 1; ESE-1
Protein Family
ETS-related transcription factor
UniProt Gene Name
ELF3
UniProt Synonym Gene Names
ESE-1
UniProt Entry Name
ELF3_HUMAN
NCBI Protein Information
ETS-related transcription factor Elf-3

UniProt Comments for Elf3

ELF3: Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development. Belongs to the ETS family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; Motility/polarity/chemotaxis; DNA-binding

Chromosomal Location of Human Ortholog: 1q32.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; transcription coactivator activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; mammary gland involution; epidermis development; extracellular matrix organization and biogenesis; blastocyst development; epithelial cell differentiation; positive regulation of transcription, DNA-dependent; multicellular organismal development; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; inflammatory response
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Research Articles on Elf3

1. ELF3 was demonstrated to form a positive feedback loop with MAPK pathways.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Elf3 blocking peptide

 Reference Product  PubMed Publications
 ERBB2 blocking peptide  >16 publications with Elf3 and ERBB2

Pathways associated with Elf3 blocking peptide

 Products by Pathway  Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram

Diseases associated with Elf3 blocking peptide

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >17 publications with Elf3 and Breast Neoplasms
 Inflammation Antibodies  >14 publications with Elf3 and Inflammation
 Adenocarcinoma Antibodies  >9 publications with Elf3 and Adenocarcinoma
 Carcinoma, Squamous Cell Antibodies  >8 publications with Elf3 and Carcinoma, Squamous Cell
 Lung Neoplasms Antibodies  >6 publications with Elf3 and Lung Neoplasms
 Necrosis Antibodies  >5 publications with Elf3 and Necrosis
 Neoplasm Metastasis Antibodies  >4 publications with Elf3 and Neoplasm Metastasis
 Prostatic Neoplasms Antibodies  >4 publications with Elf3 and Prostatic Neoplasms
 Neoplasms, Experimental Antibodies  >4 publications with Elf3 and Neoplasms, Experimental
 Disease Models, Animal Antibodies  >3 publications with Elf3 and Disease Models, Animal

Organs/Tissues associated with Elf3 blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >11 publications with Elf3 and Embryonic Tissue
 Mammary Gland Antibodies  >11 publications with Elf3 and Mammary Gland
 Lung Antibodies  >11 publications with Elf3 and Lung
 Prostate Antibodies  >11 publications with Elf3 and Prostate
 Kidney Antibodies  >9 publications with Elf3 and Kidney
 Intestine Antibodies  >9 publications with Elf3 and Intestine
 Liver Antibodies  >6 publications with Elf3 and Liver
 Stomach Antibodies  >6 publications with Elf3 and Stomach
 Bladder Antibodies  >5 publications with Elf3 and Bladder
 Muscle Antibodies  >5 publications with Elf3 and Muscle
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