EPRS Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: EPRS Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9618715
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9618715

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

EPRS, Blocking Peptide

Full Product Name

EPRS Blocking Peptide

Product Gene Name

EPRS blocking peptide

Product Synonym Names

Bifunctional aminoacyl tRNA synthetase; Bifunctional aminoacyl-tRNA synthetase; Bifunctional glutamate/proline tRNA ligase; Cell proliferation-inducing gene 32 protein; DKFZp313B047; EARS; Eprs; GLNS; Glu pro tRNA synthetase; GLUPRORS; GluRS; Glutamate tRNA ligase; Glutamatyl prolyl tRNA synthetase; Glutaminyl tRNA synthetase; Glutamyl prolyl tRNA synthetase; Glutamyl tRNA synthetase; Glutamyl-tRNA synthetase; PARS; PIG 32; PIG32; Proliferation inducing gene 32 protein; Proliferation inducing protein 32; Proline tRNA ligase; Proline--tRNA ligase; Prolyl tRNA synthetase; Prolyl-tRNA synthetase; QARS; QPRS; SYEP_HUMAN

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

EPRS peptide (MBS9618715) is used for blocking the activity of EPRS antibody (MBS9610994)

Molecular Weight

170,591 Da

OMIM

CR933648 mRNA

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for EPRS blocking peptide

Blocking/Control

Other Notes

Small volumes of EPRS blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EPRS purchase

MBS9618715 is a blocking peptide targeting EPRS.

Additional Details

NCBI/Uniprot data below describe general gene information for EPRS. It may not necessarily be applicable to this product.

NCBI GI #

62241042

NCBI GeneID

2058

NCBI Accession #

NP_004437.2

UniProt Primary Accession #

P07814

UniProt Secondary Accession #

Q05BP6; Q05DF8; Q5DSM1; Q5H9S5; Q6PD57; Q86X73; A0AVA9; B9EGH3

UniProt Related Accession #

P07814

GenBank Nucleotide #

NP_004437.2

NCBI Official Full Name

bifunctional glutamate/proline--tRNA ligase

NCBI Official Synonym Full Names

glutamyl-prolyl-tRNA synthetase

NCBI Official Symbol

EPRS

NCBI Official Synonym Symbols

EARS; PARS; QARS; QPRS; PIG32; GLUPRORS

UniProt Protein Name

Bifunctional glutamate/proline--tRNA ligase

UniProt Synonym Protein Names

Bifunctional aminoacyl-tRNA synthetase; Cell proliferation-inducing gene 32 protein; Glutamatyl-prolyl-tRNA synthetaseIncluding the following 2 domains:Glutamate--tRNA ligase (EC:6.1.1.17)Alternative name(s):Glutamyl-tRNA synthetase; GluRS

UniProt Gene Name

EPRS

UniProt Synonym Gene Names

GLNS; PARS; QARS; QPRS; GluRS

NCBI Protein Information

bifunctional glutamate/proline--tRNA ligase

NCBI Summary for EPRS

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined. [provided by RefSeq, Jul 2008]

UniProt Comments for EPRS

Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

Research Articles on EPRS

1. analysis of the heterotetrameric complex structure of the glutathione transferase (GST) domains shared among the four MSC components, methionyl-tRNA synthetase (MRS), glutaminyl-prolyl-tRNA synthetase (EPRS), AIMP2 and AIMP3

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EPRS blocking peptide

Reference Product	PubMed Publications
KARS blocking peptide	>5 publications with EPRS and KARS
QARS blocking peptide	>4 publications with EPRS and QARS
AIMP2 blocking peptide	>3 publications with EPRS and AIMP2
RARS blocking peptide	>3 publications with EPRS and RARS
LARS blocking peptide	>3 publications with EPRS and LARS
AIMP1 blocking peptide	>3 publications with EPRS and AIMP1
MARS blocking peptide	>3 publications with EPRS and MARS
DARS blocking peptide	>2 publications with EPRS and DARS
IARS blocking peptide	>2 publications with EPRS and IARS

Pathways associated with EPRS blocking peptide

Products by Pathway	Pathway Diagram
Amino Acid Metabolism Pathway antibodies	Amino Acid Metabolism Pathway Diagram
Aminoacyl-tRNA Biosynthesis Pathway antibodies	Aminoacyl-tRNA Biosynthesis Pathway Diagram
Aminoacyl-tRNA Biosynthesis Pathway antibodies	Aminoacyl-tRNA Biosynthesis Pathway Diagram
Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies	Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies	Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
Cytosolic TRNA Aminoacylation Pathway antibodies	Cytosolic TRNA Aminoacylation Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram

Diseases associated with EPRS blocking peptide

Disease Name	Pubmed Publications
Inflammation Antibodies	>12 publications with EPRS and Inflammation
Nervous System Diseases Antibodies	>11 publications with EPRS and Nervous System Diseases
Drug-Related Side Effects and Adverse Reactions Antibodies	>8 publications with EPRS and Drug-Related Side Effects and Adverse Reactions
Heart Diseases Antibodies	>5 publications with EPRS and Heart Diseases
Carcinoma Antibodies	>5 publications with EPRS and Carcinoma
Poisoning Antibodies	>5 publications with EPRS and Poisoning
Lung Neoplasms Antibodies	>4 publications with EPRS and Lung Neoplasms
Adenocarcinoma Antibodies	>4 publications with EPRS and Adenocarcinoma
Neurotoxicity Syndromes Antibodies	>4 publications with EPRS and Neurotoxicity Syndromes
Pain Antibodies	>3 publications with EPRS and Pain

Organs/Tissues associated with EPRS blocking peptide

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>19 publications with EPRS and Blood
Brain Antibodies	>12 publications with EPRS and Brain
Lung Antibodies	>10 publications with EPRS and Lung
Heart Antibodies	>7 publications with EPRS and Heart
Vascular Antibodies	>6 publications with EPRS and Vascular
Bone Antibodies	>5 publications with EPRS and Bone
Skin Antibodies	>4 publications with EPRS and Skin
Kidney Antibodies	>3 publications with EPRS and Kidney
Eye Antibodies	>3 publications with EPRS and Eye
Prostate Antibodies	>2 publications with EPRS and Prostate