Fosb Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: Fosb Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9616802
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9616802

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FosB, Blocking Peptide

Full Product Name

FosB Blocking Peptide

Product Gene Name

FosB blocking peptide

Product Synonym Names

Activator protein 1; AP 1; DKFZp686C0818; FBJ murine osteosarcoma viral oncogene homolog B; fosB; FOSB_HUMAN; G0/G1 switch regulatory protein 3; G0S3; GOS 3; GOS B; GOS3; GOSB; MGC42291; Oncogene FOS B; Oncogene FOSB; Protein fos B; Protein fosB

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

FosB peptide (MBS9616802) is used for blocking the activity of FosB antibody (MBS9601270)

Molecular Weight

35,928 Da

Chromosome Location

Chromosome: 19; NC_000019.9 (45971253..45978437). Location: 19q13.32

OMIM

164772

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for FosB blocking peptide

Blocking/Control

Other Notes

Small volumes of FosB blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FosB purchase

MBS9616802 is a blocking peptide targeting FosB.

Additional Details

NCBI/Uniprot data below describe general gene information for FosB. It may not necessarily be applicable to this product.

NCBI GI #

166999783

NCBI GeneID

2354

NCBI Accession #

NP_001107643.1

UniProt Primary Accession #

P53539

UniProt Secondary Accession #

A8K9K5; A8VJE1; A8VJE6; A8VJF0; A8VJF3; A8VJF7; A8VJG1; A8VJG5; A8VJG9; E7EPR6; E9PHJ3

UniProt Related Accession #

P53539

GenBank Nucleotide #

NM_001114171.1

NCBI Official Full Name

protein fosB isoform 2

NCBI Official Synonym Full Names

FBJ murine osteosarcoma viral oncogene homolog B

NCBI Official Symbol

FOSB

NCBI Official Synonym Symbols

AP-1; G0S3; GOS3; GOSB

UniProt Protein Name

Protein fosB

UniProt Synonym Protein Names

G0/G1 switch regulatory protein 3

Protein Family

Metallothiol transferase

UniProt Gene Name

FOSB

UniProt Synonym Gene Names

G0S3

UniProt Entry Name

FOSB_HUMAN

NCBI Protein Information

protein fosB; activator protein 1; G0/G1 switch regulatory protein 3

NCBI Summary for FosB

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for FosB

FosB: FosB interacts with Jun proteins enhancing their DNA binding activity. Heterodimer. Belongs to the bZIP family. Fos subfamily.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; double-stranded DNA binding; transcription factor activity; transcription factor binding

Biological Process: response to drug; transcription from RNA polymerase II promoter; response to cAMP; response to mechanical stimulus; response to morphine; female pregnancy; negative regulation of transcription from RNA polymerase II promoter; response to progesterone stimulus; response to corticosterone stimulus; cellular response to hormone stimulus

Research Articles on FosB

1. AP-1 protein induction during monopoiesis favors C/EBP: AP-1 heterodimers over C/EBP homodimerization and stimulates FosB transcription.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FosB blocking peptide

Reference Product	PubMed Publications
JUNB blocking peptide	>196 publications with FosB and JUNB
JUND blocking peptide	>167 publications with FosB and JUND

Pathways associated with FosB blocking peptide

Products by Pathway	Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram
Cocaine Addiction Pathway antibodies	Cocaine Addiction Pathway Diagram
Cocaine Addiction Pathway antibodies	Cocaine Addiction Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram
TGF-beta Receptor Signaling Pathway antibodies	TGF-beta Receptor Signaling Pathway Diagram

Diseases associated with FosB blocking peptide

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>75 publications with FosB and Nervous System Diseases
Disease Models, Animal Antibodies	>58 publications with FosB and Disease Models, Animal
Brain Diseases Antibodies	>58 publications with FosB and Brain Diseases
Drug Toxicity Antibodies	>52 publications with FosB and Drug Toxicity
Movement Disorders Antibodies	>40 publications with FosB and Movement Disorders
Poisoning Antibodies	>34 publications with FosB and Poisoning
Dyskinesia, Drug-Induced Antibodies	>32 publications with FosB and Dyskinesia, Drug-Induced
Seizures Antibodies	>20 publications with FosB and Seizures
Epilepsy Antibodies	>19 publications with FosB and Epilepsy
Cocaine-Related Disorders Antibodies	>17 publications with FosB and Cocaine-Related Disorders

Organs/Tissues associated with FosB blocking peptide

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>332 publications with FosB and Brain
Blood Antibodies	>77 publications with FosB and Blood
Muscle Antibodies	>38 publications with FosB and Muscle
Bone Antibodies	>34 publications with FosB and Bone
Liver Antibodies	>21 publications with FosB and Liver
Heart Antibodies	>20 publications with FosB and Heart
Lung Antibodies	>14 publications with FosB and Lung
Eye Antibodies	>11 publications with FosB and Eye
Embryonic Tissue Antibodies	>10 publications with FosB and Embryonic Tissue
Connective Tissue Antibodies	>9 publications with FosB and Connective Tissue