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FSHB Antibody (Center T70) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9226341

Stimulates development of follicle and spermatogenesis in the reproductive organs. More details

$455 / 0.5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FSHB, Blocking Peptide
Full Product Name
FSHB Antibody (Center T70) Blocking Peptide
Product Gene Name
FSHB blocking peptide
Product Synonym Names
Follitropin subunit beta; Follicle-stimulating hormone beta subunit; FSH-B; FSH-beta; Follitropin beta chain; FSHB
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of human FSHB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
FSHB peptide (MBS9226341) is used for blocking the activity of FSHB antibody (MBS9207390)
Molecular Weight
14,700 Da
OMIM
136530
Cellular Location
Secreted.

Other Notes

Small volumes of FSHB blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FSHB purchase

MBS9226341 is a blocking peptide targeting FSHB. Also known as FSHB Antibody (Center T70) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for FSHB. It may not necessarily be applicable to this product.

NCBI GI #
120552
NCBI GeneID
2488
NCBI Accession #
P01225.2
UniProt Primary Accession #
P01225
UniProt Secondary Accession #
Q14D61; A2TF08; A5JVV3
UniProt Related Accession #
P01225
NCBI Official Full Name
Follitropin subunit beta
NCBI Official Synonym Full Names
follicle stimulating hormone beta subunit
NCBI Official Symbol
FSHB
NCBI Official Synonym Symbols
HH24
UniProt Protein Name
Follitropin subunit beta
UniProt Synonym Protein Names
Follicle-stimulating hormone beta subunit; FSH-B; FSH-beta; Follitropin beta chain
Protein Family
Follitropin
UniProt Gene Name
FSHB
UniProt Synonym Gene Names
FSH-B; FSH-beta
UniProt Entry Name
FSHB_HUMAN
NCBI Protein Information
follitropin subunit beta

NCBI Summary for FSHB

The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
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UniProt Comments for FSHB

FSHB: Stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle- stimulating hormone deficiency (IFSHD). Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men. Belongs to the glycoprotein hormones subunit beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: cytoplasm; extracellular region

Molecular Function: follicle-stimulating hormone activity; hormone activity; protein binding

Biological Process: female gamete generation; female pregnancy; peptide hormone processing; progesterone biosynthetic process; signal transduction; transforming growth factor beta receptor signaling pathway

Disease: Follicle-stimulating Hormone Deficiency, Isolated
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Research Articles on FSHB

1. The FSHB -211G>T variant attenuates serum FSH levels in the supraphysiological gonadotropin setting of Klinefelter syndrome

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FSHB blocking peptide

 Reference Product  PubMed Publications
 FSHR blocking peptide  >40 publications with FSHB and FSHR
 CGA blocking peptide  >34 publications with FSHB and CGA
 INHA blocking peptide  >4 publications with FSHB and INHA
 INHBB blocking peptide  >3 publications with FSHB and INHBB
 INHBA blocking peptide  >1 publications with FSHB and INHBA

Pathways associated with FSHB blocking peptide

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 FSH Signaling Pathway antibodies  FSH Signaling Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Glycoprotein Hormones Pathway antibodies  Glycoprotein Hormones Pathway Diagram
 GnRH Signaling Pathway antibodies  GnRH Signaling Pathway Diagram
 GnRH Signaling Pathway antibodies  GnRH Signaling Pathway Diagram
 Hormone Ligand-binding Receptors Pathway antibodies  Hormone Ligand-binding Receptors Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram

Diseases associated with FSHB blocking peptide

 Disease Name  Pubmed Publications
 Infertility, Male Antibodies  >25 publications with FSHB and Infertility, Male
 Infertility, Female Antibodies  >15 publications with FSHB and Infertility, Female
 Kidney Diseases Antibodies  >10 publications with FSHB and Kidney Diseases
 Hypogonadism Antibodies  >8 publications with FSHB and Hypogonadism
 Nervous System Diseases Antibodies  >5 publications with FSHB and Nervous System Diseases
 Oligospermia Antibodies  >3 publications with FSHB and Oligospermia
 Breast Neoplasms Antibodies  >2 publications with FSHB and Breast Neoplasms
 Hypertension Antibodies  >1 publications with FSHB and Hypertension
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with FSHB and Prenatal Exposure Delayed Effects
 Follicle-stimulating hormone deficiency, isolated Antibodies  >1 publications with FSHB and Follicle-stimulating hormone deficiency, isolated

Organs/Tissues associated with FSHB blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >103 publications with FSHB and Brain
 Pituitary Gland Antibodies  >90 publications with FSHB and Pituitary Gland
 Testis Antibodies  >34 publications with FSHB and Testis
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