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GEM Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9622457

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GEM, Blocking Peptide
Full Product Name
GEM Blocking Peptide
Product Gene Name
GEM blocking peptide
Product Synonym Names
GTP binding mitogen induced T cell protein; GTP binding protein expressed in mitogen stimulated T cells; GTP binding protein GEM; GTP binding protein overexpressed in skeletal muscle; Kinase inducible Ras like protein; KIR; MGC26294; RAS like protein KIR
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.
Purity/Purification
The purity is >90%,tested by HPLC and MS.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
GEM peptide (MBS9622457) is used for blocking the activity of GEM antibody (MBS9603739)
Molecular Weight
33,949 Da
OMIM
U10550 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Notes
For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for GEM blocking peptide
Blocking/Control

Other Notes

Small volumes of GEM blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GEM purchase

MBS9622457 is a blocking peptide targeting GEM.

Additional Details

NCBI/Uniprot data below describe general gene information for GEM. It may not necessarily be applicable to this product.

NCBI GI #
4885263
NCBI GeneID
2669
NCBI Accession #
NP_005252.1
UniProt Primary Accession #
P55040
UniProt Secondary Accession #
B2RA31
UniProt Related Accession #
P55040
GenBank Nucleotide #
NM_005261.3
NCBI Official Full Name
GTP-binding protein GEM
NCBI Official Synonym Full Names
GTP binding protein overexpressed in skeletal muscle
NCBI Official Symbol
GEM
NCBI Official Synonym Symbols
KIR
UniProt Protein Name
GTP-binding protein GEM
UniProt Synonym Protein Names
GTP-binding mitogen-induced T-cell protein; RAS-like protein KIR
Protein Family
GLABRA2 expression modulator
UniProt Gene Name
GEM
UniProt Synonym Gene Names
KIR
NCBI Protein Information
GTP-binding protein GEM

NCBI Summary for GEM

The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
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UniProt Comments for GEM

GEM: Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Belongs to the small GTPase superfamily. RGK family.

Protein type: G protein; G protein, monomeric; G protein, monomeric, RGK

Chromosomal Location of Human Ortholog: 8q22.1

Cellular Component: internal side of plasma membrane; midbody; spindle midzone

Molecular Function: GDP binding; GTP binding; GTPase activity; magnesium ion binding; protein binding

Biological Process: cell surface receptor linked signal transduction; chromosome organization and biogenesis; immune response; metaphase plate congression; mitosis; signal transduction
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Research Articles on GEM

1. These findings demonstrate a new role of Gem/Gmip/RhoA signaling in cortical actin regulation during early mitotic stages.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GEM blocking peptide

 Reference Product  PubMed Publications
 GMIP blocking peptide  >7 publications with GEM and GMIP
 KIF9 blocking peptide  >2 publications with GEM and KIF9
 KIR2DL1 blocking peptide  >1 publications with GEM and KIR2DL1

Diseases associated with GEM blocking peptide

 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >164 publications with GEM and Lung Neoplasms
 Lung Diseases Antibodies  >156 publications with GEM and Lung Diseases
 Neutropenia Antibodies  >153 publications with GEM and Neutropenia
 Disease Models, Animal Antibodies  >119 publications with GEM and Disease Models, Animal
 Liver Neoplasms Antibodies  >113 publications with GEM and Liver Neoplasms
 Cardiovascular Diseases Antibodies  >113 publications with GEM and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >109 publications with GEM and Nervous System Diseases
 Neoplasms, Experimental Antibodies  >108 publications with GEM and Neoplasms, Experimental
 Anemia Antibodies  >80 publications with GEM and Anemia
 Liver Diseases Antibodies  >80 publications with GEM and Liver Diseases

Organs/Tissues associated with GEM blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >365 publications with GEM and Blood
 Liver Antibodies  >204 publications with GEM and Liver
 Lung Antibodies  >199 publications with GEM and Lung
 Brain Antibodies  >97 publications with GEM and Brain
 Bone Antibodies  >92 publications with GEM and Bone
 Pancreas Antibodies  >77 publications with GEM and Pancreas
 Vascular Antibodies  >75 publications with GEM and Vascular
 Muscle Antibodies  >70 publications with GEM and Muscle
 Heart Antibodies  >59 publications with GEM and Heart
 Skin Antibodies  >57 publications with GEM and Skin
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