GPR48 Blocking Peptide – Cat# MBS9627028

GPR48 Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: GPR48 Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9627028
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9627028

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GPR48, Blocking Peptide

Full Product Name

GPR48 Blocking Peptide

Product Gene Name

GPR48 blocking peptide

Product Synonym Names

BNMD17; G protein coupled receptor 48; G-protein coupled receptor 48; GPR48; Leucine-rich repeat-containing G protein-coupled receptor 4; Leucine-rich repeat-containing G-protein coupled receptor 4; LGR4; LGR4_HUMAN

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

GPR48 peptide (MBS9627028) is used for blocking the activity of GPR48 antibody (MBS9608316)

Molecular Weight

101,667 Da

OMIM

606666

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for GPR48 blocking peptide

Blocking/Control

Other Notes

Small volumes of GPR48 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPR48 purchase

MBS9627028 is a blocking peptide targeting GPR48.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR48. It may not necessarily be applicable to this product.

NCBI GI #

1078569891

NCBI GeneID

55366

NCBI Accession #

NP_001333361.1

UniProt Primary Accession #

Q9BXB1

UniProt Secondary Accession #

Q8N537; Q9NYD1; A6NCH3; G5E9B3

UniProt Related Accession #

Q9BXB1

GenBank Nucleotide #

NM_001346432.1

NCBI Official Full Name

leucine-rich repeat-containing G-protein coupled receptor 4 isoform 2

NCBI Official Synonym Full Names

leucine rich repeat containing G protein-coupled receptor 4

NCBI Official Symbol

LGR4

NCBI Official Synonym Symbols

GPR48; BNMD17

UniProt Protein Name

Leucine-rich repeat-containing G-protein coupled receptor 4

UniProt Synonym Protein Names

G-protein coupled receptor 48

UniProt Gene Name

LGR4

UniProt Synonym Gene Names

GPR48

UniProt Entry Name

LGR4_HUMAN

NCBI Protein Information

leucine-rich repeat-containing G-protein coupled receptor 4

NCBI Summary for GPR48

The protein encoded by this gene is a G-protein coupled receptor that binds R-spondins and activates the Wnt signaling pathway. This Wnt signaling pathway activation is necessary for proper development of many organs of the body. [provided by RefSeq, Oct 2016]

UniProt Comments for GPR48

LGR4: a leucine-rich repeat-containing G-protein-coupled receptor. Receptor for R-spondins, potent stimulators of adult stem cell proliferation. A Wnt receptor component that enhances Wnt signaling by soluble R-spondin proteins. Plays an essential role during homeostasis of the adult mouse intestine.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 11p14-p13

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding; transmembrane receptor activity

Biological Process: osteoblast differentiation; G-protein coupled receptor protein signaling pathway; epithelial cell proliferation; positive regulation of transcription, DNA-dependent; negative regulation of cytokine secretion; male genitalia development; negative regulation of toll-like receptor signaling pathway; innate immune response; spermatogenesis; circadian regulation of gene expression; bone remodeling; negative regulation of transcription, DNA-dependent; bone mineralization

Disease: Bone Mineral Density Quantitative Trait Locus 17

Research Articles on GPR48

1. the host protein leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is essential for VSV and VSV-G pseudotyped lentivirus (VSVG-LV) to infect susceptible cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GPR48 blocking peptide

Products by Pathway	Pathway Diagram
Circadian Rythm Related Genes Pathway antibodies	Circadian Rythm Related Genes Pathway Diagram
Regulation Of FZD By Ubiquitination Pathway antibodies	Regulation Of FZD By Ubiquitination Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By Wnt Pathway antibodies	Signaling By Wnt Pathway Diagram
TCF Dependent Signaling In Response To WNT Pathway antibodies	TCF Dependent Signaling In Response To WNT Pathway Diagram