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GPS2 Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5400975

MBS5400975 is a blocking peptide targeting GPS2. Antigenic Blocking Peptide G protein pathway suppressor 2 Antibody More details

$315 / 0.25 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GPS2, Blocking Peptide
Full Product Name
GPS2 Blocking Peptide
Product Gene Name
Product Synonym Names
AMF 1 antibody; G protein pathway suppressor 2 antibody; GPS 2 antibody
Specificity
Widely expressed.
Preparation and Storage
Store at-20 degree C for long term storage.
OMIM
601935
Immunogen
Synthetic peptide taken within amino acid region 250-300 on human G protein pathway suppressor 2 protein.
Structure
Coiled coil
Subcellular Location
Nucleus, Cytosol

Product Categories/Family for GPS2 blocking peptide

Applications Tested/Suitable for GPS2 blocking peptide
Immunodepletion, Immunocompetition
Application Notes for GPS2 blocking peptide
WB: 1:2500-1:5000

Other Notes

Small volumes of GPS2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPS2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G protein pathway suppressor 2
NCBI Official Synonym Full Names
G protein pathway suppressor 2
NCBI Official Symbol
GPS2
NCBI Official Synonym Symbols
AMF-1
UniProt Protein Name
G protein pathway suppressor 2
UniProt Gene Name
GPS2
UniProt Synonym Gene Names
GPS-2
UniProt Entry Name
GPS2_HUMAN
NCBI Protein Information
G protein pathway suppressor 2

NCBI Summary for GPS2

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008]
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UniProt Comments for GPS2

GPS2: Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction.

Protein type: Inhibitor; G protein regulator, misc.; Cell cycle regulation; Transcription, coactivator/corepressor; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 17p13

Cellular Component: nucleoplasm; transcriptional repressor complex

Molecular Function: protein binding; transcription corepressor activity; GTPase inhibitor activity

Biological Process: negative regulation of JNK cascade; establishment and/or maintenance of chromatin architecture; JNK cascade; negative regulation of transcription from RNA polymerase II promoter; cell cycle; inactivation of MAPK activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GPS2 blocking peptide

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