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HES7 Antibody (N-Term) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9228357

Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for… More details

$455 / 0.5 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
HES7, Blocking Peptide
Full Product Name
HES7 Antibody (N-term) Blocking Peptide
Product Gene Name
Product Synonym Gene Name
BHLHB37
Product Synonym Names
Transcription factor HES-7; hHes7; Class B basic helix-loop-helix protein 37; bHLHb37; Hairy and enhancer of split 7; bHLH factor Hes7; HES7; BHLHB37
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
HES7 peptide (MBS9228357) is used for blocking the activity of HES7 antibody (MBS9205829)
Molecular Weight
25,280 Da
OMIM
608059
Cellular Location
Nucleus.

Other Notes

Small volumes of HES7 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HES7 purchase

MBS9228357 is a blocking peptide targeting HES7. Also known as HES7 Antibody (N-term) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for HES7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Transcription factor HES-7
NCBI Official Synonym Full Names
hes family bHLH transcription factor 7
NCBI Official Symbol
HES7
NCBI Official Synonym Symbols
SCDO4; bHLHb37
UniProt Protein Name
Transcription factor HES-7
UniProt Synonym Protein Names
Class B basic helix-loop-helix protein 37; bHLHb37; Hairy and enhancer of split 7; bHLH factor Hes7
Protein Family
UniProt Gene Name
HES7
UniProt Synonym Gene Names
BHLHB37; hHes7; bHLHb37
UniProt Entry Name
HES7_HUMAN
NCBI Protein Information
transcription factor HES-7

NCBI Summary for HES7

This gene encodes a member of the hairy and enhancer of split family of bHLH transcription factors. The mouse ortholog of this gene is regulated by Notch signaling. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton. A mutation in this gene has been shown to result in spondylocostal dysostosis. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
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UniProt Comments for HES7

HES7: Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation. Defects in HES7 are the cause of spondylocostal dysostosis type 4 (SCDO4). A rare condition of variable severity characterized by vertebral and costal anomalies. The main feature include dwarfism, vertebral fusion, hemivertebrae, posterior rib fusion, reduced rib number, and other rib malformations.

Chromosomal Location of Human Ortholog: 17p13.1

Disease: Spondylocostal Dysostosis 4, Autosomal Recessive
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with HES7 blocking peptide

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