Humanin Blocking Peptide

Name: Humanin Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS543828
Price: 315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS543828

Plays a role as a neuroprotective factor. Protects against death induced by multiple different familial Alzheimer disease genes and beta amyloid proteins in Alzheimer disease. Suppresses apoptosis by binding to BAX and preventing the translocation of BAX from… More details

$315 / 0.25 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Humanin (MTRNR2L2), Blocking Peptide

Full Product Name

Humanin Peptide

Product Gene Name

MTRNR2L2 blocking peptide

Product Synonym Names

HN; HUNIN; MT-RNR2 antibody

Form/Format

Antigenic Blocking Peptide

Concentration

0.5 ug/ul in antibody stabilization buffer (lot specific)

Preparation and Storage

-20 degree C for long term storage

Antibody/Peptide Pairs

Humanin peptide (MBS543828) is used for blocking the activity of Humanin antibody (MBS541832)

Antibody/Peptide Pairs

Humanin peptide (MBS543828) is used for blocking the activity of Humanin antibody (MBS541833)

Molecular Weight

3,081 Da

Immunogen

Synthetic peptide corresponding to amino acid region 5-24 on Humanin protein.
Sequence: GFSCLLLSTTATDLPVKRRT

Expression

Expressed in the heart, skeletal muscles, kidney and liver. Lesser but significant expression is observed in the brain and the gastrointestinal tract. Expressed in the AD brain, where it is found in some of the large intact neurons of the occipital lobes and small and round reactive glial cells in the hippocampus.

Molecular Function

Receptor antagonist activity; Apoptosis; Leukocyte chemotaxis

Structure

Largely unstructured in aqueous solution.

Subcellular Location

Secreted; Cytoplasm

Applications Tested/Suitable for MTRNR2L2 blocking peptide

Immunodepletion, Immunocompetition

Application Notes for MTRNR2L2 blocking peptide

ELISA: 1:10,000
Western Blot: 1:500

Other Notes

Small volumes of MTRNR2L2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MTRNR2L2 purchase

MBS543828 is a blocking peptide targeting MTRNR2L2. Also known as Humanin Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for MTRNR2L2. It may not necessarily be applicable to this product.

NCBI GI #

299473783

NCBI GeneID

100462981

NCBI Accession #

NP_001177399.1

UniProt Primary Accession #

Q8IVG9

UniProt Related Accession #

P0CJ69

GenBank Nucleotide #

NM_001190470.1

NCBI Official Full Name

humanin-like 2

NCBI Official Synonym Full Names

MT-RNR2-like 2

NCBI Official Symbol

MTRNR2L2

NCBI Official Synonym Symbols

HN2

UniProt Protein Name

Humanin-like 2

UniProt Synonym Protein Names

MT-RNR2-like protein 2

Protein Family

Humanin

UniProt Gene Name

MTRNR2L2

UniProt Synonym Gene Names

HN2

UniProt Entry Name

HMN2_HUMAN

NCBI Protein Information

humanin-like 2

UniProt Comments for MTRNR2L2

MTRNR2L2: Plays a role as a neuroprotective and antiapoptotic factor. Belongs to the humanin family.

Chromosomal Location of Human Ortholog: 5q14.1

Cellular Component: cytoplasm; extracellular region

Research Articles on MTRNR2L2

1. Data suggest that humanin (the first small peptide of a putative set of mitochondrial derived peptides) exhibits strong cytoprotective actions against various stress and disease models.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.