Il-34 Blocking Peptide

Name: Il-34 Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS5401371
Price: 315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5401371

MBS5401371 is a blocking peptide targeting IL-34. Antigenic Blocking Peptide Interleukin-34 Antibody More details

$315 / 0.25 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IL-34, Blocking Peptide

Full Product Name

IL-34 Blocking Peptide

Product Gene Name

IL-34 blocking peptide

Preparation and Storage

Store at -20 degree C for long term storage

Antibody/Peptide Pairs

IL-34 peptide (MBS5401371) is used for blocking the activity of IL-34 antibody (MBS5401136)

Antibody/Peptide Pairs

IL-34 peptide (MBS5401371) is used for blocking the activity of IL-34 antibody (MBS5401137)

Molecular Weight

27,482 Da

Chromosome Location

Chromosome: 16; NC_000016.9 (70613798..70694585). Location: 16q22.1

OMIM

612081

Immunogen

Interleukin-34

Product Categories/Family for IL-34 blocking peptide

Biomolecule

Applications Tested/Suitable for IL-34 blocking peptide

Immunodepletion, Immunocompetition

Other Notes

Small volumes of IL-34 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-34. It may not necessarily be applicable to this product.

NCBI GI #

289666752

NCBI GeneID

146433

NCBI Accession #

NP_001166243.1

UniProt Primary Accession #

Q6ZMJ4

UniProt Secondary Accession #

Q8N6L2; B2RC28; B2Z4A8; B2ZC70

UniProt Related Accession #

Q6ZMJ4

GenBank Nucleotide #

NM_001172772.1

NCBI Official Full Name

interleukin-34 isoform 1

NCBI Official Synonym Full Names

interleukin 34

NCBI Official Symbol

IL34

NCBI Official Synonym Symbols

IL-34; C16orf77

UniProt Protein Name

Interleukin-34

UniProt Gene Name

IL34

UniProt Synonym Gene Names

C16orf77; IL-34

UniProt Entry Name

IL34_HUMAN

NCBI Protein Information

interleukin-34

NCBI Summary for IL-34

Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008]

UniProt Comments for IL-34

IL34: Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Belongs to the IL-34 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Cell cycle regulation; Cytokine

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; macrophage colony stimulating factor receptor binding

Biological Process: positive regulation of cell proliferation; innate immune response; positive regulation of protein amino acid phosphorylation; inflammatory response

Research Articles on IL-34

1. the feline CSF-1R was cloned and the responsiveness to CSF-1 and IL-34 from a range of species, was examined.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IL-34 blocking peptide

Reference Product	PubMed Publications
CSF1R blocking peptide	>3 publications with IL-34 and CSF1R