IRF9 Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: IRF9 Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9617727
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9617727

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IRF9, Blocking Peptide

Full Product Name

IRF9 Blocking Peptide

Product Gene Name

IRF9 blocking peptide

Product Synonym Names

IFN alpha responsive transcription factor subunit; IFN-alpha-responsive transcription factor subunit; Interferon regulatory factor 9; interferon stimulated transcription factor 3; Interferon-stimulated gene factor 3 gamma; interferon-stimulated transcription factor 3, gamma 48kDa; IRF 9; IRF-9; Irf9; IRF9_HUMAN; ISGF 3 gamma; ISGF-3 gamma; ISGF3; ISGF3 p48 subunit; ISGF3G; OTTHUMP00000164692; OTTHUMP00000164693; p48; Transcriptional regulator ISGF3 subunit gamma

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

IRF9 peptide (MBS9617727) is used for blocking the activity of IRF9 antibody (MBS9613646)

Molecular Weight

393

OMIM

147574

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for IRF9 blocking peptide

Blocking/Control

Other Notes

Small volumes of IRF9 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IRF9 purchase

MBS9617727 is a blocking peptide targeting IRF9.

Additional Details

NCBI/Uniprot data below describe general gene information for IRF9. It may not necessarily be applicable to this product.

NCBI GI #

266392

NCBI GeneID

10379

NCBI Accession #

Q00978.1

UniProt Primary Accession #

Q00978

UniProt Secondary Accession #

D3DS61

UniProt Related Accession #

Q00978

NCBI Official Full Name

Interferon regulatory factor 9

NCBI Official Synonym Full Names

interferon regulatory factor 9

NCBI Official Symbol

IRF9

NCBI Official Synonym Symbols

p48; IRF-9; ISGF3; ISGF3G

UniProt Protein Name

Interferon regulatory factor 9

UniProt Synonym Protein Names

IFN-alpha-responsive transcription factor subunit; ISGF3 p48 subunit; Interferon-stimulated gene factor 3 gamma; ISGF-3 gamma; Transcriptional regulator ISGF3 subunit gamma

Protein Family

Interferon regulatory factor

UniProt Gene Name

IRF9

UniProt Synonym Gene Names

ISGF3G; IRF-9; ISGF-3 gamma

UniProt Entry Name

IRF9_HUMAN

NCBI Protein Information

interferon regulatory factor 9; ISGF-3 gamma; ISGF3 p48 subunit; interferon-stimulated gene factor 3 gamma; transcriptional regulator ISGF3 subunit gamma; IFN-alpha-responsive transcription factor subunit; interferon-stimulated transcription factor 3, gam

UniProt Comments for IRF9

IRF9: Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. Belongs to the IRF family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: nucleoplasm; cytoplasm; cytosol; nucleus

Molecular Function: protein binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; cell surface receptor linked signal transduction; regulation of transcription, DNA-dependent; cytokine and chemokine mediated signaling pathway; interferon type I biosynthetic process; defense response to virus

Research Articles on IRF9

1. IL6 is an inducer of IRF9 expression in prostate cancer and a sensitizer for the antiproliferative effects of IFNalpha2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IRF9 blocking peptide

Reference Product	PubMed Publications
STAT1 blocking peptide	>168 publications with IRF9 and STAT1
STAT2 blocking peptide	>126 publications with IRF9 and STAT2
IRF7 blocking peptide	>30 publications with IRF9 and IRF7
ISG15 blocking peptide	>12 publications with IRF9 and ISG15
MX1 blocking peptide	>7 publications with IRF9 and MX1
IFIT3 blocking peptide	>6 publications with IRF9 and IFIT3
IFIT2 blocking peptide	>4 publications with IRF9 and IFIT2
IFIT1 blocking peptide	>3 publications with IRF9 and IFIT1
IFI6 blocking peptide	>2 publications with IRF9 and IFI6

Pathways associated with IRF9 blocking peptide

Products by Pathway	Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Hepatitis C Pathway antibodies	Hepatitis C Pathway Diagram
Hepatitis C Pathway antibodies	Hepatitis C Pathway Diagram
Herpes Simplex Infection Pathway antibodies	Herpes Simplex Infection Pathway Diagram
Herpes Simplex Infection Pathway antibodies	Herpes Simplex Infection Pathway Diagram
IFN-gamma Pathway antibodies	IFN-gamma Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram
Interferon Signaling Pathway antibodies	Interferon Signaling Pathway Diagram

Diseases associated with IRF9 blocking peptide

Disease Name	Pubmed Publications
Inflammation Antibodies	>19 publications with IRF9 and Inflammation
Liver Diseases Antibodies	>16 publications with IRF9 and Liver Diseases
Necrosis Antibodies	>14 publications with IRF9 and Necrosis
Carcinoma, Hepatocellular Antibodies	>8 publications with IRF9 and Carcinoma, Hepatocellular
Cardiovascular Diseases Antibodies	>7 publications with IRF9 and Cardiovascular Diseases
Cell Transformation, Neoplastic Antibodies	>6 publications with IRF9 and Cell Transformation, Neoplastic
Brain Diseases Antibodies	>5 publications with IRF9 and Brain Diseases
Heart Diseases Antibodies	>3 publications with IRF9 and Heart Diseases
Fibrosis Antibodies	>3 publications with IRF9 and Fibrosis
Atherosclerosis Antibodies	>3 publications with IRF9 and Atherosclerosis

Organs/Tissues associated with IRF9 blocking peptide

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>35 publications with IRF9 and Blood
Liver Antibodies	>20 publications with IRF9 and Liver
Lung Antibodies	>7 publications with IRF9 and Lung
Skin Antibodies	>7 publications with IRF9 and Skin
Brain Antibodies	>7 publications with IRF9 and Brain
Vascular Antibodies	>6 publications with IRF9 and Vascular
Muscle Antibodies	>5 publications with IRF9 and Muscle
Kidney Antibodies	>5 publications with IRF9 and Kidney
Bone Antibodies	>3 publications with IRF9 and Bone
Heart Antibodies	>3 publications with IRF9 and Heart