KCNT2 Antibody (C-Term) Blocking Peptide

Name: KCNT2 Antibody (C-Term) Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS9217546
Price: 455 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9217546

Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (By… More details

$455 / 0.5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

KCNT2, Blocking Peptide

Full Product Name

KCNT2 Antibody (C-term) Blocking peptide

Product Gene Name

KCNT2 blocking peptide

Product Synonym Gene Name

SLICK

Product Synonym Names

Potassium channel subfamily T member 2; Sequence like an intermediate conductance potassium channel subunit; Sodium and chloride-activated ATP-sensitive potassium channel Slo21; KCNT2; SLICK

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

KCNT2 peptide (MBS9217546) is used for blocking the activity of KCNT2 antibody (MBS9208260)

Molecular Weight

120,830 Da

OMIM

610044

Cellular Location

Cell membrane; Multi-pass membrane protein

Other Notes

Small volumes of KCNT2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KCNT2 purchase

MBS9217546 is a blocking peptide targeting KCNT2. Also known as KCNT2 Antibody (C-term) Blocking peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for KCNT2. It may not necessarily be applicable to this product.

NCBI GI #

41349443

NCBI GeneID

343450

NCBI Accession #

NP_940905.2

UniProt Primary Accession #

Q6UVM3

UniProt Secondary Accession #

Q3SY59; Q5VTN1; Q6ZMT3

UniProt Related Accession #

Q6UVM3

GenBank Nucleotide #

NM_198503.3

NCBI Official Full Name

potassium channel subfamily T member 2 isoform 1

NCBI Official Synonym Full Names

potassium sodium-activated channel subfamily T member 2

NCBI Official Symbol

KCNT2

NCBI Official Synonym Symbols

SLICK; KCa4.2; SLO2.1

UniProt Protein Name

Potassium channel subfamily T member 2

UniProt Synonym Protein Names

Sequence like an intermediate conductance potassium channel subunit; Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1

Protein Family

Potassium channel subfamily

UniProt Gene Name

KCNT2

UniProt Synonym Gene Names

SLICK

UniProt Entry Name

KCNT2_HUMAN

NCBI Protein Information

potassium channel subfamily T member 2

UniProt Comments for KCNT2

KCNT2: Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane. Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. Belongs to the potassium channel family. Calcium- activated (TC 1.A.1.3) subfamily. KCa4.2/KCNT2 sub-subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, potassium; Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1q31.3

Cellular Component: voltage-gated potassium channel complex

Molecular Function: calcium-activated potassium channel activity; voltage-gated potassium channel activity

Research Articles on KCNT2

1. Together these results suggest that hydrophobic interactions between residues in S5 and the C-terminal end of the pore helix stabilize Slo2.1 channels in a closed state.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with KCNT2 blocking peptide

Disease Name	Pubmed Publications
Fibrosis Antibodies	>1 publications with KCNT2 and Fibrosis

Organs/Tissues associated with KCNT2 blocking peptide

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>6 publications with KCNT2 and Brain