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LASS2 Peptide - N-Terminal Region Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3226075

LASS2 is a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. This gene… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LASS2, Blocking Peptide
Full Product Name
LASS2 Peptide - N-terminal region
Product Gene Name
Product Synonym Gene Name
CerS2; FLJ10243; L3; MGC987; SP260; TMSG1; LASS2
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Antibody/Peptide Pairs
LASS2 peptide (MBS3226075) is used for blocking the activity of LASS2 antibody (MBS3201046)
Molecular Weight
45kDa
OMIM
606920

Product Categories/Family for LASS2 blocking peptide

Applications Tested/Suitable for LASS2 blocking peptide
Immunohistochemistry (IHC), Western Blot (WB)

Other Notes

Small volumes of LASS2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LASS2 purchase

MBS3226075 is a blocking peptide targeting LASS2. Also known as LASS2 Peptide - N-terminal region.

Additional Details

NCBI/Uniprot data below describe general gene information for LASS2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ceramide synthase 2
NCBI Official Synonym Full Names
ceramide synthase 2
NCBI Official Symbol
CERS2
NCBI Official Synonym Symbols
L3; LASS2; SP260; TMSG1
UniProt Protein Name
Ceramide synthase 2
UniProt Synonym Protein Names
LAG1 longevity assurance homolog 2; SP260; Tumor metastasis-suppressor gene 1 protein
UniProt Gene Name
CERS2
UniProt Synonym Gene Names
LASS2; TMSG1; CerS2
UniProt Entry Name
CERS2_HUMAN
NCBI Protein Information
ceramide synthase 2

NCBI Summary for LASS2

This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
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UniProt Comments for LASS2

Function: Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis.

Subunit structure: Interacts with ATP6V0C, ASGR1, ASGR2 and SLC22A1/OCT1. Interacts with ELOV1, HSD17B12 and TECR. Ref.1 Ref.15

Subcellular location: Nucleus membrane; Multi-pass membrane protein

Potential. Endoplasmic reticulum membrane; Multi-pass membrane protein

By similarity.

Tissue specificity: Expressed in kidney, liver, brain, heart, placenta and lung. Ref.1

Sequence similarities: Contains 1 homeobox DNA-binding domain.Contains 1 TLC (TRAM/LAG1/CLN8) domain.

Sequence caution: The sequence BAA91505.1 differs from that shown. Reason: Erroneous initiation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with LASS2 blocking peptide

 Reference Product  PubMed Publications
 ATP6V0C blocking peptide  >1 publications with LASS2 and ATP6V0C
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