LIME1 Antibody (C-Term) Blocking Peptide

Name: LIME1 Antibody (C-Term) Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS9220604
Price: 455 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9220604

Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T- cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation… More details

$455 / 0.5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LIME1, Blocking Peptide

Full Product Name

LIME1 Antibody (C-term) Blocking Peptide

Product Gene Name

LIME1 blocking peptide

Product Synonym Gene Name

LIME

Product Synonym Names

Lck-interacting transmembrane adapter 1; Lck-interacting membrane protein; Lck-interacting molecule; LIME1; LIME

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

LIME1 peptide (MBS9220604) is used for blocking the activity of LIME1 antibody (MBS9210604)

Molecular Weight

20,841 Da

OMIM

609809

Cellular Location

Cell membrane; Single-pass type III membrane protein. Note: Present in lipid rafts Recruited to the immunological synapse upon conjugation of T-cell with antigen-presenting cell

Tissue Location

Expressed in peripheral blood lymphocytes, lymphoid tissues, and liver. Present in T-cells and plasma cells, and in various hematopoietic cell lines (at protein level)

Other Notes

Small volumes of LIME1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LIME1 purchase

MBS9220604 is a blocking peptide targeting LIME1. Also known as LIME1 Antibody (C-term) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for LIME1. It may not necessarily be applicable to this product.

NCBI GI #

74752630

NCBI GeneID

54923

NCBI Accession #

Q9H400.1

UniProt Primary Accession #

Q9H400

UniProt Secondary Accession #

Q5JWJ2; Q6XYB3; Q9NX69; E1P5K5; E1P5K6

UniProt Related Accession #

Q9H400

NCBI Official Full Name

Lck-interacting transmembrane adapter 1

NCBI Official Synonym Full Names

Lck interacting transmembrane adaptor 1

NCBI Official Symbol

LIME1

NCBI Official Synonym Symbols

LIME; dJ583P15.4

UniProt Protein Name

Lck-interacting transmembrane adapter 1

UniProt Synonym Protein Names

Lck-interacting molecule

Protein Family

Lck-interacting transmembrane adapter

UniProt Gene Name

LIME1

UniProt Synonym Gene Names

LIME; Lck-interacting membrane protein

UniProt Entry Name

LIME1_HUMAN

NCBI Protein Information

lck-interacting transmembrane adapter 1

NCBI Summary for LIME1

This gene encodes a transmembrane adaptor protein that links the T and B-cell receptor stimulation to downstream signaling pathways via its association with the Src family kinases Lck and Lyn, respectively. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2015]

UniProt Comments for LIME1

LIME1: Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T- cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 20q13.3

Cellular Component: extracellular space

Research Articles on LIME1

1. these results establish LIME as a transmembrane adaptor protein linking TCR stimulation to IS formation and integrin activation through activation of Vav(Vav guanine nucleotide exchange factor)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with LIME1 blocking peptide

Products by Pathway	Pathway Diagram
B Cell Receptor Signaling Pathway antibodies	B Cell Receptor Signaling Pathway Diagram

Organs/Tissues associated with LIME1 blocking peptide

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>1 publications with LIME1 and Lung