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LPPR4 Antibody (C-Term) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9225451

Hydrolyzes lysophosphatidic acid (LPA). Facilitates axonal outgrowth during development and regenerative sprouting. In the outgrowing axons acts as an ecto-enzyme and attenuates phospholipid-induced axon collapse in neurons and facilitates outgrowth in the… More details

$455 / 0.5 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
LPPR4, Blocking Peptide
Full Product Name
LPPR4 Antibody (C-term) Blocking Peptide
Product Gene Name
LPPR4 blocking peptide
Product Synonym Gene Name
KIAA0455; PRG1
Product Synonym Names
Lipid phosphate phosphatase-related protein type 4; Brain-specific phosphatidic acid phosphatase-like protein 1; Plasticity-related gene 1 protein; PRG-1; LPPR4; KIAA0455; PRG1
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
LPPR4 peptide (MBS9225451) is used for blocking the activity of LPPR4 antibody (MBS9214566)
Molecular Weight
76,554 Da
OMIM
607813
Cellular Location
Membrane; Multi-pass membrane protein
Tissue Location
Specifically expressed in neurons.

Other Notes

Small volumes of LPPR4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LPPR4 purchase

MBS9225451 is a blocking peptide targeting LPPR4. Also known as LPPR4 Antibody (C-term) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for LPPR4. It may not necessarily be applicable to this product.

NCBI GI #
33636722
NCBI GeneID
9890
NCBI Accession #
NP_055654
UniProt Primary Accession #
Q7Z2D5
UniProt Secondary Accession #
O75043; Q5T9R9; Q86XQ5; Q8N3F1; Q96MP0; E7EPS1
UniProt Related Accession #
Q7Z2D5
GenBank Nucleotide #
NM_014839.4
NCBI Official Full Name
phospholipid phosphatase-related protein type 4 isoform 1
NCBI Official Synonym Full Names
phospholipid phosphatase related 4
NCBI Official Symbol
PLPPR4
NCBI Official Synonym Symbols
LPR4; PHP1; PRG1; LPPR4; PRG-1
UniProt Protein Name
Phospholipid phosphatase-related protein type 4
UniProt Synonym Protein Names
Brain-specific phosphatidic acid phosphatase-like protein 1
UniProt Gene Name
PLPPR4
UniProt Synonym Gene Names
PRG-1
UniProt Entry Name
PLPR4_HUMAN
NCBI Protein Information
phospholipid phosphatase-related protein type 4

NCBI Summary for LPPR4

The protein encoded by this gene belongs to the lipid phosphate phosphatase (LPP) family. LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions. This protein is specifically expressed in neurons. It is located in the membranes of outgrowing axons and has been shown to be important for axonal outgrowth during development and regenerative sprouting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
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UniProt Comments for LPPR4

LPPR4: Hydrolyzes lysophosphatidic acid (LPA). Facilitates axonal outgrowth during development and regenerative sprouting. In the outgrowing axons acts as an ecto-enzyme and attenuates phospholipid-induced axon collapse in neurons and facilitates outgrowth in the hippocampus. Belongs to the PA-phosphatase related phosphoesterase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Phosphatase, lipid; Cell development/differentiation; EC 3.1.3.4; Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1p21.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: lipid phosphatase activity; phosphatidate phosphatase activity

Biological Process: axonogenesis; phospholipid dephosphorylation; phospholipid metabolic process; signal transduction
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Research Articles on LPPR4

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with LPPR4 blocking peptide

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Lysosphingolipid And LPA Receptors Pathway antibodies  Lysosphingolipid And LPA Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Triacylglycerol Biosynthesis Pathway antibodies  Triacylglycerol Biosynthesis Pathway Diagram
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