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Phospho-MARK3 (Thr507) Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9616035

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MARK3, Blocking Peptide
Full Product Name
Phospho-MARK3 (Thr507) Blocking Peptide
Product Gene Name
MARK3 blocking peptide
Product Synonym Gene Name
MARK1, MARK3, MARK4
Product Synonym Names
C-TAK1; Cdc25C associated protein kinase 1; Cdc25C-associated protein kinase 1; cTAK1; ELKL motif kinase 2; EMK-2; Emk2; ETK 1; KIAA4230; KP78; MAP microtubule affinity regulating kinase 3; MAP/microtubule affinity-regulating kinase 3; Mark3; MARK3_HUMAN; Par 1a; PAR1A; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Serine threonine protein kinase p78; Serine/threonine-protein kinase p78; SerThr protein kinase PAR 1; FLJ90097; KIAA1860; MAP/microtubule affinity regulating kinase 4; MAP/microtubule affinity regulating kinase 4L; MAP/microtubule affinity regulating kinase 4; MAP/microtubule affinity regulating kinase like 1; MAP/microtubule affinity-regulating kinase 4; MAP/microtubule affinity-regulating kinase-like 1; MARK 4; MARK 4L; MARK L1; MARK4; MARK4 serine/threonine protein kinase; MARK4 serine/threonine protein kinase; MARK4_HUMAN; MARK4S; MARKL 1; MARKL1; Nbla00650; Putative protein product of Nbla00650; KIAA1477; MAP/microtubule affinity regulating kinase 1; MAP/microtubule affinity-regul
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.
Purity/Purification
The purity is >90%,tested by HPLC and MS.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
MARK3 (Thr507) peptide (MBS9616035) is used for blocking the activity of MARK3 (Thr507) antibody (MBS9612754)
Molecular Weight
84,911 Da
OMIM
606511
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Notes
For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for MARK3 blocking peptide
Blocking/Control

Other Notes

Small volumes of MARK3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MARK3 purchase

MBS9616035 is a blocking peptide targeting MARK3. Also known as Phospho-MARK3 (Thr507) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for MARK3. It may not necessarily be applicable to this product.

NCBI GI #
153791472
NCBI GeneID
4139
NCBI Accession #
NP_061120.3
UniProt Primary Accession #
Q9P0L2
UniProt Secondary Accession #
P27448; Q96L34
UniProt Related Accession #
Q9P0L2
GenBank Nucleotide #
NM_018650.4
NCBI Official Full Name
serine/threonine-protein kinase MARK1 isoform 2
NCBI Official Synonym Full Names
MAP/microtubule affinity-regulating kinase 1
NCBI Official Symbol
MARK1
NCBI Official Synonym Symbols
MARK; Par1c; Par-1c
UniProt Protein Name
Serine/threonine-protein kinase MARK1
UniProt Synonym Protein Names
MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c
Protein Family
MAP/microtubule affinity-regulating kinase
UniProt Gene Name
MARK1
UniProt Synonym Gene Names
Par-1c; Par1c
UniProt Entry Name
MARK1_HUMAN
NCBI Protein Information
serine/threonine-protein kinase MARK1; PAR1 homolog c

UniProt Comments for MARK3

MARK1: a member of the CAMKL family of protein kinases. The MARK group of kinases is apparently involved in the control of cell polarity, microtubule stability and cancer. MARK1 forms a tight association with Tau in neurofibrillary tangles in Alzheimer disease tissue.

Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.26; EC 2.7.11.1; Protein kinase, CAMK; CAMK group; CAMKL family; MARK subfamily

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: microtubule cytoskeleton; cytoskeleton; cytoplasm; plasma membrane

Molecular Function: protein serine/threonine kinase activity; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; tau-protein kinase activity; magnesium ion binding; ATP binding

Biological Process: Wnt receptor signaling pathway; neuron migration; cytoskeleton organization and biogenesis; protein amino acid phosphorylation
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Research Articles on MARK3

1. the positioning of MARK/Par-1 at the crosstalk of regulating cytoskeletal dynamics allows its participation in neuronal polarity decisions. [review]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MARK3 blocking peptide

 Reference Product  PubMed Publications
 MARK2 blocking peptide  >79 publications with MARK3 and MARK2
 MAP2 blocking peptide  >8 publications with MARK3 and MAP2
 MAP4 blocking peptide  >6 publications with MARK3 and MAP4
 STK11 blocking peptide  >5 publications with MARK3 and STK11
 MAPT blocking peptide  >1 publications with MARK3 and MAPT

Pathways associated with MARK3 blocking peptide

 Products by Pathway  Pathway Diagram
 Regulation Of Microtubule Cytoskeleton Pathway antibodies  Regulation Of Microtubule Cytoskeleton Pathway Diagram

Diseases associated with MARK3 blocking peptide

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >19 publications with MARK3 and Nervous System Diseases
 Brain Diseases Antibodies  >17 publications with MARK3 and Brain Diseases
 Inflammation Antibodies  >9 publications with MARK3 and Inflammation
 Necrosis Antibodies  >7 publications with MARK3 and Necrosis
 Carcinoma, Hepatocellular Antibodies  >5 publications with MARK3 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >4 publications with MARK3 and Liver Diseases
 Anemia Antibodies  >4 publications with MARK3 and Anemia
 Fibrosis Antibodies  >4 publications with MARK3 and Fibrosis
 Liver Cirrhosis Antibodies  >3 publications with MARK3 and Liver Cirrhosis
 Stomach Neoplasms Antibodies  >3 publications with MARK3 and Stomach Neoplasms

Organs/Tissues associated with MARK3 blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >38 publications with MARK3 and Brain
 Heart Antibodies  >16 publications with MARK3 and Heart
 Lung Antibodies  >14 publications with MARK3 and Lung
 Bone Antibodies  >8 publications with MARK3 and Bone
 Kidney Antibodies  >6 publications with MARK3 and Kidney
 Skin Antibodies  >5 publications with MARK3 and Skin
 Stomach Antibodies  >4 publications with MARK3 and Stomach
 Nerve Antibodies  >4 publications with MARK3 and Nerve
 Bladder Antibodies  >3 publications with MARK3 and Bladder
 Intestine Antibodies  >2 publications with MARK3 and Intestine
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