NDUFAF2 Blocking Peptide – Cat# MBS9621881

NDUFAF2 Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: NDUFAF2 Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9621881
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9621881

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NDUFAF2, Blocking Peptide

Full Product Name

NDUFAF2 Blocking Peptide

Product Gene Name

NDUFAF2 blocking peptide

Product Synonym Names

B17.2 like; B17.2-like; B17.2L; FLJ22398; MIMIT_HUMAN; Mimitin; Mimitin mitochondrial, mitochondrial; MMTN; Myc induced mitochondrial protein; Myc-induced mitochondrial protein; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor 2; NADH dehydrogenase (ubiquinone) complex I, assembly factor 2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; NDUFA12 like; NDUFA12 like protein; NDUFA12-like protein; NDUFA12L; NDUFAF2; OTTHUMP00000161882; OTTHUMP00000221703

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

NDUFAF2 peptide (MBS9621881) is used for blocking the activity of NDUFAF2 antibody (MBS9611928)

Molecular Weight

19,856 Da

OMIM

252010

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for NDUFAF2 blocking peptide

Blocking/Control

Other Notes

Small volumes of NDUFAF2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NDUFAF2 purchase

MBS9621881 is a blocking peptide targeting NDUFAF2.

Additional Details

NCBI/Uniprot data below describe general gene information for NDUFAF2. It may not necessarily be applicable to this product.

NCBI GI #

29789409

NCBI GeneID

91942

NCBI Accession #

NP_777549.1

UniProt Primary Accession #

Q8N183

UniProt Secondary Accession #

A8K5I1

UniProt Related Accession #

Q8N183

GenBank Nucleotide #

NP_777549.1

NCBI Official Full Name

mimitin, mitochondrial

NCBI Official Synonym Full Names

NADH dehydrogenase (ubiquinone) complex I, assembly factor 2

NCBI Official Symbol

NDUFAF2

NCBI Official Synonym Symbols

MMTN; B17.2L; mimitin; NDUFA12L

UniProt Protein Name

Mimitin, mitochondrial

UniProt Synonym Protein Names

B17.2-like; B17.2L; Myc-induced mitochondrial protein; MMTN; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; NDUFA12-like protein

Protein Family

Mimitin

UniProt Gene Name

NDUFAF2

UniProt Synonym Gene Names

NDUFA12L; B17.2L; MMTN

UniProt Entry Name

MIMIT_HUMAN

NCBI Protein Information

mimitin, mitochondrial; Myc-induced mitochondrial protein; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2; NDUFA12-like protein

NCBI Summary for NDUFAF2

NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene cause progressive encephalopathy resulting from mitochondrial complex I deficiency. [provided by RefSeq, Jul 2008]

UniProt Comments for NDUFAF2

NDUFAF2: Acts as a molecular chaperone for mitochondrial complex I assembly. Defects in NDUFAF2 are a cause of mitochondrial complex I deficiency (MT-C1D). A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. Belongs to the complex I NDUFA12 subunit family.

Chromosomal Location of Human Ortholog: 5q12.1

Cellular Component: mitochondrion

Molecular Function: NADH dehydrogenase (ubiquinone) activity

Disease: Leigh Syndrome; Mitochondrial Complex I Deficiency

Research Articles on NDUFAF2

1. Within the clinical spectrum of Leigh disease, patients with mutations in NDUFAF2 present with a distinct clinical pattern with predominantly brainstem involvement on MRI

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NDUFAF2 blocking peptide

Reference Product	PubMed Publications
NDUFA12 blocking peptide	>3 publications with NDUFAF2 and NDUFA12
NDUFS4 blocking peptide	>2 publications with NDUFAF2 and NDUFS4
NDUFAF4 blocking peptide	>1 publications with NDUFAF2 and NDUFAF4
C20orf7 blocking peptide	>1 publications with NDUFAF2 and C20orf7
MAP1S blocking peptide	>1 publications with NDUFAF2 and MAP1S
MYC blocking peptide	>1 publications with NDUFAF2 and MYC

Pathways associated with NDUFAF2 blocking peptide

Products by Pathway	Pathway Diagram
Validated Targets Of C-MYC Transcriptional Activation Pathway antibodies	Validated Targets Of C-MYC Transcriptional Activation Pathway Diagram

Diseases associated with NDUFAF2 blocking peptide

Disease Name	Pubmed Publications
Leigh Disease Antibodies	>2 publications with NDUFAF2 and Leigh Disease
Brain Diseases, Metabolic, Inborn Antibodies	>2 publications with NDUFAF2 and Brain Diseases, Metabolic, Inborn
Genital Diseases, Male Antibodies	>1 publications with NDUFAF2 and Genital Diseases, Male
Prostatic Diseases Antibodies	>1 publications with NDUFAF2 and Prostatic Diseases
Congenital Abnormalities Antibodies	>1 publications with NDUFAF2 and Congenital Abnormalities
Mitochondrial complex I deficiency Antibodies	>1 publications with NDUFAF2 and Mitochondrial complex I deficiency

Organs/Tissues associated with NDUFAF2 blocking peptide

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>4 publications with NDUFAF2 and Brain
Muscle Antibodies	>2 publications with NDUFAF2 and Muscle
Skin Antibodies	>2 publications with NDUFAF2 and Skin
Pancreas Antibodies	>1 publications with NDUFAF2 and Pancreas
Lung Antibodies	>1 publications with NDUFAF2 and Lung
Liver Antibodies	>1 publications with NDUFAF2 and Liver
Prostate Antibodies	>1 publications with NDUFAF2 and Prostate
Heart Antibodies	>1 publications with NDUFAF2 and Heart
Embryonic Tissue Antibodies	>1 publications with NDUFAF2 and Embryonic Tissue
Kidney Antibodies	>1 publications with NDUFAF2 and Kidney