NEK6 Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: NEK6 Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9627372
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9627372

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NEK6, Blocking Peptide

Full Product Name

NEK6 Blocking Peptide

Product Gene Name

NEK6 blocking peptide

Product Synonym Names

Highly similar to cell cycle protein kinase CDC5/MSD2; NEK6; NEK6_HUMAN; Never in mitosis A-related kinase 6; NIMA (Never In Mitosis Gene A) Related Kinase 6; NimA related protein kinase 6; NimA-related protein kinase 6; Protein kinase SID6 1512; Protein kinase SID6-1512; Putative serine threonine protein kinase; Serine/threonine protein kinase Nek6; Serine/threonine-protein kinase Nek6; SID6 1512; SID61512

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

NEK6 peptide (MBS9627372) is used for blocking the activity of NEK6 antibody (MBS9608660)

Molecular Weight

63.0 kDa

OMIM

604884

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for NEK6 blocking peptide

Blocking/Control

Other Notes

Small volumes of NEK6 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NEK6 purchase

MBS9627372 is a blocking peptide targeting NEK6.

Additional Details

NCBI/Uniprot data below describe general gene information for NEK6. It may not necessarily be applicable to this product.

NCBI GI #

222418622

NCBI GeneID

10783

NCBI Accession #

NP_001138473.1

UniProt Primary Accession #

Q9HC98

UniProt Secondary Accession #

Q5TBG3; Q5TBG9; Q6FG86; Q6IAR3; Q96E83; Q9ULX2; B7Z2D9

UniProt Related Accession #

Q9HC98

GenBank Nucleotide #

NM_001145001.2

NCBI Official Full Name

serine/threonine-protein kinase Nek6 isoform 1

NCBI Official Synonym Full Names

NIMA-related kinase 6

NCBI Official Symbol

NEK6

NCBI Official Synonym Symbols

SID6-1512

UniProt Protein Name

Serine/threonine-protein kinase Nek6

UniProt Synonym Protein Names

Never in mitosis A-related kinase 6; NimA-related protein kinase 6; Protein kinase SID6-1512

Protein Family

Serine/threonine-protein kinase

UniProt Gene Name

NEK6

UniProt Synonym Gene Names

NimA-related protein kinase 6

UniProt Entry Name

NEK6_HUMAN

NCBI Protein Information

serine/threonine-protein kinase Nek6

NCBI Summary for NEK6

The protein encoded by this gene is a kinase required for progression through the metaphase portion of mitosis. Inhibition of the encoded protein can lead to apoptosis. This protein also can enhance tumorigenesis by suppressing tumor cell senescence. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

UniProt Comments for NEK6

NEK6: a protein kinase of the NEK family. Important in mitosis. May regulate spindle function.

Protein type: Protein kinase, Other; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Other group; NEK family

Chromosomal Location of Human Ortholog: 9q33.3-q34.11

Cellular Component: spindle pole; microtubule; cytoplasm; microtubule organizing center; nuclear speck; cytosol; nucleus

Molecular Function: protein serine/threonine kinase activity; protein binding; signal transducer activity; kinesin binding; magnesium ion binding; protein kinase binding; ATP binding

Biological Process: mitosis; positive regulation of I-kappaB kinase/NF-kappaB cascade; apoptosis; protein amino acid autophosphorylation; regulation of mitotic cell cycle; regulation of mitotic metaphase/anaphase transition; mitotic nuclear envelope disassembly; cytokinesis; spindle assembly; signal transduction; protein amino acid phosphorylation; chromosome segregation; peptidyl-serine phosphorylation; mitotic cell cycle; G2/M transition DNA damage checkpoint

Research Articles on NEK6

1. Nek6 is also a critical signaling molecule that helps prevent cardiac hypertrophy and inhibits the Akt signaling pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NEK6 blocking peptide

Reference Product	PubMed Publications
NEK9 blocking peptide	>14 publications with NEK6 and NEK9
KIF11 blocking peptide	>2 publications with NEK6 and KIF11
PLK1 blocking peptide	>2 publications with NEK6 and PLK1

Pathways associated with NEK6 blocking peptide

Products by Pathway	Pathway Diagram
Activation Of NIMA Kinases NEK9, NEK6, NEK7 Pathway antibodies	Activation Of NIMA Kinases NEK9, NEK6, NEK7 Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
M Phase Pathway antibodies	M Phase Pathway Diagram
Mitotic Prophase Pathway antibodies	Mitotic Prophase Pathway Diagram
Nuclear Envelope Breakdown Pathway antibodies	Nuclear Envelope Breakdown Pathway Diagram
Nuclear Pore Complex (NPC) Disassembly Pathway antibodies	Nuclear Pore Complex (NPC) Disassembly Pathway Diagram

Diseases associated with NEK6 blocking peptide

Disease Name	Pubmed Publications
Carcinoma, Hepatocellular Antibodies	>5 publications with NEK6 and Carcinoma, Hepatocellular
Liver Diseases Antibodies	>4 publications with NEK6 and Liver Diseases
Liver Neoplasms Antibodies	>4 publications with NEK6 and Liver Neoplasms
Cell Transformation, Neoplastic Antibodies	>4 publications with NEK6 and Cell Transformation, Neoplastic
Lung Neoplasms Antibodies	>2 publications with NEK6 and Lung Neoplasms
Neoplasms, Experimental Antibodies	>2 publications with NEK6 and Neoplasms, Experimental
Cardiovascular Diseases Antibodies	>1 publications with NEK6 and Cardiovascular Diseases
Heart Diseases Antibodies	>1 publications with NEK6 and Heart Diseases
Fibrosis Antibodies	>1 publications with NEK6 and Fibrosis
Hypertrophy Antibodies	>1 publications with NEK6 and Hypertrophy

Organs/Tissues associated with NEK6 blocking peptide

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>7 publications with NEK6 and Liver
Muscle Antibodies	>3 publications with NEK6 and Muscle
Lung Antibodies	>3 publications with NEK6 and Lung
Spleen Antibodies	>2 publications with NEK6 and Spleen
Heart Antibodies	>2 publications with NEK6 and Heart
Embryonic Tissue Antibodies	>2 publications with NEK6 and Embryonic Tissue
Brain Antibodies	>2 publications with NEK6 and Brain
Uterus Antibodies	>1 publications with NEK6 and Uterus
Testis Antibodies	>1 publications with NEK6 and Testis
Stomach Antibodies	>1 publications with NEK6 and Stomach