NSE Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: NSE Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9626557
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9626557

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NSE, Blocking Peptide

Full Product Name

NSE Blocking Peptide

Product Gene Name

NSE blocking peptide

Product Synonym Names

2 phospho D glycerate hydrolyase; 2-phospho-D-glycerate hydro-lyase; Eno 2; ENO2; ENOG; ENOG_HUMAN; Enolase 2 (gamma, neuronal); Enolase 2; Enolase 2 gamma neuronal; Enolase2; Epididymis secretory protein Li 279; Gamma enolase; Gamma-enolase; HEL S 279; Neural enolase; Neuron specific enolase; Neuron specific gamma enolase; Neuron-specific enolase; neuronal enriched enolase; Neurone specific enolase; NSE

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

NSE peptide (MBS9626557) is used for blocking the activity of NSE antibody (MBS9607844)

Molecular Weight

47,269 Da

Chromosome Location

Chromosome: 12; NC_000012.11 (7023614..7032859). Location: 12p13

OMIM

131360

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for NSE blocking peptide

Blocking/Control

Other Notes

Small volumes of NSE blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NSE purchase

MBS9626557 is a blocking peptide targeting NSE.

Additional Details

NCBI/Uniprot data below describe general gene information for NSE. It may not necessarily be applicable to this product.

NCBI GI #

5803011

NCBI GeneID

2026

NCBI Accession #

NP_001966.1

UniProt Primary Accession #

P09104

UniProt Secondary Accession #

Q96J33; B7Z2X9

UniProt Related Accession #

P09104

GenBank Nucleotide #

NM_001975.2

NCBI Official Full Name

gamma-enolase

NCBI Official Synonym Full Names

enolase 2 (gamma, neuronal)

NCBI Official Symbol

ENO2

NCBI Official Synonym Symbols

NSE

UniProt Protein Name

Gamma-enolase

UniProt Synonym Protein Names

2-phospho-D-glycerate hydro-lyase; Enolase 2; Neural enolase; Neuron-specific enolase

Protein Family

Gamma-enolase

UniProt Gene Name

ENO2

UniProt Synonym Gene Names

NSE

UniProt Entry Name

ENOG_HUMAN

NCBI Protein Information

gamma-enolase; neural enolase; neuron-specific enolase; neurone-specific enolase; neuron specific gamma enolase; 2-phospho-D-glycerate hydrolyase; 2-phospho-D-glycerate hydro-lyase

NCBI Summary for NSE

This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008]

UniProt Comments for NSE

ENO2: an enzyme with 2-phospho-D-glycerate hydro-lyase activity. One of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates.

Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; Lyase; EC 4.2.1.11

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: extracellular space; photoreceptor inner segment; phosphopyruvate hydratase complex; plasma membrane; perikaryon; cytosol

Molecular Function: magnesium ion binding; phosphopyruvate hydratase activity

Biological Process: glycolysis; carbohydrate metabolic process; glucose metabolic process; pathogenesis; gluconeogenesis

Research Articles on NSE

1. NSE may be a novel marker of disease aggressiveness as well as a prognostic factor for non-germinal center B-cell type subtype of diffuse large B-cell lymphoma in the era of rituximab.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NSE blocking peptide

Reference Product	PubMed Publications
HK1 blocking peptide	>2 publications with NSE and HK1

Pathways associated with NSE blocking peptide

Products by Pathway	Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
Gluconeogenesis Pathway antibodies	Gluconeogenesis Pathway Diagram
Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway antibodies	Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway Diagram
Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway antibodies	Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway Diagram
Glucose Metabolism Pathway antibodies	Glucose Metabolism Pathway Diagram
Glycolysis Pathway antibodies	Glycolysis Pathway Diagram
Glycolysis (Embden-Meyerhof Pathway), Glucose => Pyruvate antibodies	Glycolysis (Embden-Meyerhof Pathway), Glucose => Pyruvate Diagram
Glycolysis (Embden-Meyerhof Pathway), Glucose => Pyruvate antibodies	Glycolysis (Embden-Meyerhof Pathway), Glucose => Pyruvate Diagram
Glycolysis / Gluconeogenesis Pathway antibodies	Glycolysis / Gluconeogenesis Pathway Diagram

Diseases associated with NSE blocking peptide

Disease Name	Pubmed Publications
Neoplasms Antibodies	>12 publications with NSE and Neoplasms
Nervous System Diseases Antibodies	>4 publications with NSE and Nervous System Diseases
Brain Diseases Antibodies	>4 publications with NSE and Brain Diseases
Adenocarcinoma Antibodies	>3 publications with NSE and Adenocarcinoma
Lung Diseases Antibodies	>2 publications with NSE and Lung Diseases
Inflammation Antibodies	>2 publications with NSE and Inflammation
Kidney Diseases Antibodies	>2 publications with NSE and Kidney Diseases
Hypertension Antibodies	>2 publications with NSE and Hypertension
Uterine Cervical Neoplasms Antibodies	>2 publications with NSE and Uterine Cervical Neoplasms
Prostatic Neoplasms Antibodies	>2 publications with NSE and Prostatic Neoplasms

Organs/Tissues associated with NSE blocking peptide

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>14 publications with NSE and Brain
Blood Antibodies	>8 publications with NSE and Blood
Muscle Antibodies	>7 publications with NSE and Muscle
Intestine Antibodies	>4 publications with NSE and Intestine
Lung Antibodies	>4 publications with NSE and Lung
Skin Antibodies	>3 publications with NSE and Skin
Kidney Antibodies	>3 publications with NSE and Kidney
Bone Antibodies	>3 publications with NSE and Bone
Liver Antibodies	>3 publications with NSE and Liver
Embryonic Tissue Antibodies	>3 publications with NSE and Embryonic Tissue