PDHX Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: PDHX Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9621153
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9621153

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PDHX, Blocking Peptide

Full Product Name

PDHX Blocking Peptide

Product Gene Name

PDHX blocking peptide

Product Synonym Names

Dihydrolipoamide dehydrogenase binding protein of pyruvate dehydrogenase complex; Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex; DLDBP; E3 binding protein; E3-binding protein; E3BP; Lipoyl containing pyruvate dehydrogenase complex component X; Lipoyl-containing pyruvate dehydrogenase complex component X; mitochondrial; ODPX_HUMAN; OPDX; PDHX; PDX 1; PDX1; Pro X; proX; Pyruvate dehydrogenase complex component X; Pyruvate dehydrogenase complex lipoyl containing component X; Pyruvate dehydrogenase complex, E3 binding protein subunit; Pyruvate dehydrogenase protein X component; Pyruvate dehydrogenase protein X component mitochondrial

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

PDHX peptide (MBS9621153) is used for blocking the activity of PDHX antibody (MBS9603676)

Molecular Weight

51,460 Da

OMIM

phenotype 608769

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for PDHX blocking peptide

Blocking/Control

Other Notes

Small volumes of PDHX blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDHX purchase

MBS9621153 is a blocking peptide targeting PDHX.

Additional Details

NCBI/Uniprot data below describe general gene information for PDHX. It may not necessarily be applicable to this product.

NCBI GI #

203098816

NCBI GeneID

8050

NCBI Accession #

NP_001128496.1

UniProt Primary Accession #

O00330

UniProt Secondary Accession #

O60221; Q96FV8; Q99783; B4DW62; D3DR11; E9PB14; E9PBP7

UniProt Related Accession #

O00330

GenBank Nucleotide #

NM_001135024.1

NCBI Official Full Name

pyruvate dehydrogenase protein X component, mitochondrial isoform 2

NCBI Official Synonym Full Names

pyruvate dehydrogenase complex component X

NCBI Official Symbol

PDHX

NCBI Official Synonym Symbols

E3BP; OPDX; PDX1; proX; DLDBP

UniProt Protein Name

Pyruvate dehydrogenase protein X component, mitochondrial

UniProt Synonym Protein Names

Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex; E3-binding protein; E3BP; Lipoyl-containing pyruvate dehydrogenase complex component X; proX

Protein Family

Pyruvate dehydrogenase complex

UniProt Gene Name

PDHX

UniProt Synonym Gene Names

PDX1; E3BP

UniProt Entry Name

ODPX_HUMAN

NCBI Protein Information

pyruvate dehydrogenase protein X component, mitochondrial

UniProt Comments for PDHX

PDHX: a mitochondrial protein required for anchoring dihydrolipoamide dehydrogenase (E3) to the pyruvate dehydrogenase complexes (PDHC) of eukaryotes. This specific binding is essential for a PDHC function. Eukaryotic pyruvate dehydrogenase complexes are organized about a core consisting of the oligomeric dihydrolipoamide acetyl-transferase (E2), around which are arranged multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide dehydrogenase (E3), and protein X bound by non-covalent bonds. Belongs to the 2-oxoacid dehydrogenase family. Contains 1 lipoyl-binding domain.

Protein type: Mitochondrial

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: mitochondrial matrix

Molecular Function: transferase activity, transferring acyl groups

Biological Process: cellular metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate; pyruvate metabolic process

Disease: Pyruvate Dehydrogenase E3-binding Protein Deficiency

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PDHX blocking peptide

Products by Pathway	Pathway Diagram
Glycolysis And Gluconeogenesis Pathway antibodies	Glycolysis And Gluconeogenesis Pathway Diagram
Glyoxylate Metabolism And Glycine Degradation Pathway antibodies	Glyoxylate Metabolism And Glycine Degradation Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram
Pyruvate Metabolism Pathway antibodies	Pyruvate Metabolism Pathway Diagram
Pyruvate Metabolism And Citric Acid (TCA) Cycle Pathway antibodies	Pyruvate Metabolism And Citric Acid (TCA) Cycle Pathway Diagram
Regulation Of Pyruvate Dehydrogenase (PDH) Complex Pathway antibodies	Regulation Of Pyruvate Dehydrogenase (PDH) Complex Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By Retinoic Acid Pathway antibodies	Signaling By Retinoic Acid Pathway Diagram

Diseases associated with PDHX blocking peptide

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>15 publications with PDHX and Brain Diseases
Liver Diseases Antibodies	>14 publications with PDHX and Liver Diseases
Pyruvate Dehydrogenase E3-Binding Protein Deficiency Antibodies	>11 publications with PDHX and Pyruvate Dehydrogenase E3-Binding Protein Deficiency
Intellectual Disability Antibodies	>10 publications with PDHX and Intellectual Disability
Cardiovascular Diseases Antibodies	>3 publications with PDHX and Cardiovascular Diseases
Inflammation Antibodies	>2 publications with PDHX and Inflammation
Necrosis Antibodies	>2 publications with PDHX and Necrosis
Hepatitis Antibodies	>1 publications with PDHX and Hepatitis
Heart Defects, Congenital Antibodies	>1 publications with PDHX and Heart Defects, Congenital
Fibrosis Antibodies	>1 publications with PDHX and Fibrosis

Organs/Tissues associated with PDHX blocking peptide

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>15 publications with PDHX and Liver
Blood Antibodies	>11 publications with PDHX and Blood
Muscle Antibodies	>4 publications with PDHX and Muscle
Skin Antibodies	>4 publications with PDHX and Skin
Heart Antibodies	>4 publications with PDHX and Heart
Brain Antibodies	>3 publications with PDHX and Brain
Thyroid Antibodies	>2 publications with PDHX and Thyroid
Nerve Antibodies	>1 publications with PDHX and Nerve
Eye Antibodies	>1 publications with PDHX and Eye
Larynx Antibodies	>1 publications with PDHX and Larynx