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PELO Antibody Antigenic Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS544239

Antigenic Blocking Peptide PELOTA AntibodyIs necessary in cell division for normal chromosome segregation and genomic stability.  It may recognize stalled ribosomes and trigger endonucleolytic cleavage of the mRNA, and may hav ribonuclease activity. More details

$315 / 0.25 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PELO, Blocking Peptide
Full Product Name
PELO Antibody Antigenic Blocking Peptide
Product Gene Name
Product Synonym Names
CGI 17; pelo; pelota (Drosophila) homolog; pelota homolog; PRO1770; Protein pelota homolog antibody
Form/Format
Antigenic Blocking Peptide
Concentration
Quantity: 250 ug; Volume: 100 ul (lot specific)
Preparation and Storage
-20 degree C for long term storage
Antibody/Peptide Pairs
PELO peptide (MBS544239) is used for blocking the activity of PELO antibody (MBS543624)
Antibody/Peptide Pairs
PELO peptide (MBS544239) is used for blocking the activity of PELO antibody (MBS543625)
Molecular Weight
43,359 Da
OMIM
605757
Immunogen
Synthetic Peptide
Expression
Expressed ubiquitously
Molecular Function
Endonuclease, Hydrolase, Nuclease
Structure
The N-terminal domain has the RNA-binding Sm fold. It may harbor the endoribonuclease activity (Potential).  Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
Subcellular Location
Nuclease, Cytoplasm
Applications Tested/Suitable for PELO blocking peptide
Immunodepletion, Immunocompetition
Application Notes for PELO blocking peptide
Western Blot: 1:500

Other Notes

Small volumes of PELO blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PELO purchase

MBS544239 is a blocking peptide targeting PELO. Also known as PELO Antibody Antigenic Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for PELO. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
PELOTA
NCBI Official Synonym Full Names
pelota homolog (Drosophila)
NCBI Official Symbol
PELO
NCBI Official Synonym Symbols
CGI-17; PRO1770
UniProt Protein Name
Protein pelota homolog
Protein Family
UniProt Gene Name
PELO
UniProt Entry Name
PELO_HUMAN
NCBI Protein Information
protein pelota homolog

NCBI Summary for PELO

This gene encodes a protein which contains a conserved nuclear localization signal. The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division. [provided by RefSeq, Jul 2008]

UniProt Comments for PELO

PELO: Required for normal chromosome segregation during cell division and genomic stability. May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). Belongs to the eukaryotic release factor 1 family. Pelota subfamily.

Protein type: EC 3.1.-.-; Hydrolase

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: cytoplasm; nucleus

Molecular Function: endonuclease activity; metal ion binding; protein binding

Biological Process: cell cycle; cell division; cell proliferation; chromosome organization and biogenesis
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Research Articles on PELO

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PELO blocking peptide

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