PIGW Blocking Peptide

Name: PIGW Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS3234307
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3234307

This is a synthetic peptide designed for use in combination with anti-PIGW antibody madeTarget Description: Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI… More details

$195 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PIGW, Blocking Peptide

Full Product Name

PIGW Peptide

Product Gene Name

PIGW blocking peptide

Product Synonym Gene Name

FLJ37433; Gwt1

Form/Format

Lyophilized powder

Preparation and Storage

Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.

Antibody/Peptide Pairs

PIGW peptide (MBS3234307) is used for blocking the activity of PIGW antibody (MBS3209347)

Molecular Weight

57kDa

OMIM

AB097818 mRNA

Product Categories/Family for PIGW blocking peptide

Peptide

Applications Tested/Suitable for PIGW blocking peptide

Western Blot (WB)

Other Notes

Small volumes of PIGW blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PIGW purchase

MBS3234307 is a blocking peptide targeting PIGW. Also known as PIGW Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for PIGW. It may not necessarily be applicable to this product.

NCBI GI #

75750492

NCBI GeneID

284098

NCBI Accession #

NP_848612

UniProt Primary Accession #

Q7Z7B1

UniProt Related Accession #

Q7Z7B1

GenBank Nucleotide #

NM_178517

NCBI Official Full Name

phosphatidylinositol-glycan biosynthesis class W protein

NCBI Official Synonym Full Names

phosphatidylinositol glycan anchor biosynthesis class W

NCBI Official Symbol

PIGW

NCBI Official Synonym Symbols

Gwt1; HPMRS5

UniProt Protein Name

Phosphatidylinositol-glycan biosynthesis class W protein

Protein Family

Phosphatidylinositol-glycan biosynthesis class W protein

UniProt Gene Name

PIGW

UniProt Synonym Gene Names

PIG-W

NCBI Protein Information

phosphatidylinositol-glycan biosynthesis class W protein

NCBI Summary for PIGW

The protein encoded by this gene is an inositol acyltransferase that acylates the inositol ring of phosphatidylinositol. This occurs in the endoplasmic reticulum and is a step in the biosynthesis of glycosylphosphatidylinositol (GPI), which anchors many cell surface proteins to the membrane. Defects in this gene are a cause of the age-dependent epileptic encephalopathy West syndrome as well as a syndrome exhibiting hyperphosphatasia and cognitive disability (HPMRS5). [provided by RefSeq, Jul 2017]

UniProt Comments for PIGW

PIGW: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI- anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins. Belongs to the PIGW family.

Protein type: EC 2.3.-.-; Endoplasmic reticulum; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, integral; Membrane protein, multi-pass; Transferase

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: endoplasmic reticulum membrane; integral component of membrane

Molecular Function: O-acyltransferase activity

Biological Process: GPI anchor metabolic process; preassembly of GPI anchor in ER membrane

Disease: Hyperphosphatasia With Mental Retardation Syndrome 5

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PIGW blocking peptide

Products by Pathway	Pathway Diagram
GPI-anchor Biosynthesis, Core Oligosaccharide Pathway antibodies	GPI-anchor Biosynthesis, Core Oligosaccharide Pathway Diagram
GPI-anchor Biosynthesis, Core Oligosaccharide Pathway antibodies	GPI-anchor Biosynthesis, Core Oligosaccharide Pathway Diagram
Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies	Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram
Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies	Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway antibodies	Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway Diagram
Post-translational Protein Modification Pathway antibodies	Post-translational Protein Modification Pathway Diagram
Synthesis Of Glycosylphosphatidylinositol (GPI) Pathway antibodies	Synthesis Of Glycosylphosphatidylinositol (GPI) Pathway Diagram

Diseases associated with PIGW blocking peptide

Disease Name	Pubmed Publications
Atrophy Antibodies	>2 publications with PIGW and Atrophy
Seizures Antibodies	>1 publications with PIGW and Seizures
Nervous System Diseases Antibodies	>1 publications with PIGW and Nervous System Diseases
Anemia Antibodies	>1 publications with PIGW and Anemia

Organs/Tissues associated with PIGW blocking peptide

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>1 publications with PIGW and Liver
Brain Antibodies	>1 publications with PIGW and Brain